4-Fluorophenoxyacetic Acid (CAS: 405-79-8) stands as a versatile and crucial chemical intermediate, recognized for its significant role in advanced organic synthesis. This compound presents as a white powder, characterized by its molecular formula C8H7FO3 and a molecular weight of 170.14. With a melting point typically around 104-105 °C, its consistent physical properties make it a reliable building block for various chemical applications, particularly within the pharmaceutical and agrochemical industries.

One of the most compelling applications of 4-Fluorophenoxyacetic Acid lies in its derivatives, especially its hydrazide form, which has shown remarkable promise in cutting-edge medical research. Recent studies highlight its utility in synthesizing specialized copper(II) complexes. These novel complexes have demonstrated potent and selective cytotoxic activity against various aggressive tumor cell lines, including Sarcoma 180, melanoma B16F10, and HeLa cells. Importantly, this activity is observed with significantly lower toxicity towards non-tumorigenic cells, addressing a critical challenge in cancer therapy development: the fine line between efficacy and adverse side effects.

The mechanism of action for these advanced compounds derived from 4-Fluorophenoxyacetic Acid is particularly noteworthy. Research indicates that these complexes exert their anti-proliferative effects through multiple pathways, including inducing DNA damage, specifically causing both genomic and plasmid DNA fragmentation. Furthermore, they are shown to trigger G0/G1 cell cycle arrest, effectively halting the proliferation of cancer cells. A key aspect of their action involves the generation of reactive oxygen species (ROS) and subsequent lipid peroxidation, leading to oxidative stress within cancerous cells, which ultimately culminates in programmed cell death, or apoptosis. This multifaceted approach underscores the potential of 4-Fluorophenoxyacetic Acid as a vital precursor in the development of novel and more targeted anticancer therapeutics.

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In conclusion, 4-Fluorophenoxyacetic Acid (CAS: 405-79-8) is more than just a chemical; it is a gateway to pioneering advancements in medicinal chemistry, particularly in the critical area of cancer treatment. NINGBO INNO PHARMCHEM CO.,LTD. proudly supports these vital endeavors by supplying a product that meets stringent purity and quality specifications, contributing to the development of life-changing therapies worldwide.