In the intricate world of organic synthesis, the availability of versatile and reliable intermediates is key to innovation and efficient production. 4-Hydroxyisobenzofuran-1,3-dione, identified by CAS number 37418-88-5, emerges as a significant player in this domain. This compound, often referred to as 3-Hydroxyphthalic anhydride, serves as a critical building block for chemists aiming to construct complex molecular structures. This article explores its properties, applications, and the advantages of sourcing it from a reputable chemical supplier.

Chemical Properties and Structure

4-Hydroxyisobenzofuran-1,3-dione boasts a molecular formula of C8H4O4 and a molecular weight of 164.12. It typically presents as a white to pale yellow powder, signifying its stable solid state at room temperature. Key specifications often include a purity of 98% minimum, a melting point range of 199-202 °C, and a high boiling point of approximately 365.4 °C at standard pressure. These characteristics make it suitable for a variety of chemical reactions, including those requiring elevated temperatures or specific reaction conditions.

Key Applications in Organic Synthesis

The true value of 4-Hydroxyisobenzofuran-1,3-dione lies in its broad applicability within organic chemistry:

• Building Block for Complex Molecules: Its dual functionality—the anhydride and hydroxyl groups—allows for diverse derivatization. It can readily participate in reactions to form esters, amides, and heterocyclic systems, crucial steps in synthesizing advanced organic compounds.
• Precursor in Pharmaceutical Synthesis: As an intermediate, it plays a role in the development pathways for various pharmaceutical agents. Its structure can be incorporated into drug molecules to impart specific biological activities or improve pharmacokinetic properties. We offer this as a high-quality pharmaceutical intermediate from our China manufacturing base.
• Research and Development: In academic and industrial research settings, 4-Hydroxyisobenzofuran-1,3-dione is utilized as a biochemical reagent and a foundational compound for exploring new chemical transformations and novel material development.
• Potential in Material Science: Its unique structure makes it a candidate for incorporation into polymers or functional materials, opening avenues for innovation in material science applications.

Sourcing Excellence from a Trusted Supplier

For chemists and procurement professionals seeking to buy 4-Hydroxyisobenzofuran-1,3-dione, partnering with a reliable manufacturer is essential. We, as a leading chemical supplier based in China, provide this vital intermediate with guaranteed purity and competitive pricing. Our commitment is to ensure that you have access to the high-quality materials needed to drive your organic synthesis projects forward. We encourage you to contact us for inquiries regarding bulk orders, custom synthesis needs, and to secure a dependable supply of this indispensable chemical building block.