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4-Iodophenetole: A Versatile Chemical Intermediate for Advanced Materials

4-Iodophenetole (CAS 699-08-1): A Crucial Compound in Modern Chemistry


4-Iodophenetole, scientifically known as 1-ethoxy-4-iodobenzene, is a significant organic compound with the Chemical Abstracts Service (CAS) Registry Number 699-08-1. This versatile chemical intermediate, represented by the molecular formula C8H9IO and a molecular weight of approximately 248.06, plays a pivotal role in various advanced chemical syntheses and material science applications. NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated supplier of this high-quality substance, ensuring its availability for diverse industrial and research needs.


Comprehensive Chemical Profile and Properties


The physical and chemical characteristics of 4-Iodophenetole contribute significantly to its utility. It typically appears as a light yellow transparent liquid or pale yellowish-brown crystals, depending on temperature conditions, indicating its low melting point. Key physical properties include a melting point ranging from 25 to 28 degrees Celsius and a boiling point of 133-134 degrees Celsius at 19mm pressure. Its density is approximately 1.631 g/cm3, and it exhibits a refractive index of 1.5970. The flash point is notably high, exceeding 230 degrees Fahrenheit (or 110 degrees Celsius), underscoring its stability under appropriate conditions. Furthermore, 4-Iodophenetole is known to be soluble in methanol, facilitating its use in various solvent-based reactions.


For optimal stability and longevity, 4-Iodophenetole requires careful storage. It should be stored in a sealed container in a cool, dry place, away from oxidizing agents. As it is light sensitive, storing it in a dark environment at room temperature is highly recommended to preserve its integrity and purity over time.


Diverse Applications in Advanced Synthesis


  • Liquid Crystal Intermediates: One of the most prominent uses of 4-Iodophenetole is its role as an intermediate in the production of liquid crystals. These materials are fundamental to modern display technologies, including LCD screens used in televisions, computer monitors, and smartphones. The precise chemical structure of 4-Iodophenetole allows for the synthesis of complex molecules with specific optical and electrical properties required for liquid crystal displays.
  • Synthesis of Bis(4-ethoxyphenyl)amine: 4-Iodophenetole serves as a crucial component in the synthesis of bis(4-ethoxyphenyl)amine, an important compound in its own right. This derivative finds applications in various specialized chemical processes and material development.
  • Suzuki Reaction Participant: It is widely employed in Suzuki coupling reactions, a powerful and versatile carbon-carbon bond-forming cross-coupling reaction in organic chemistry. The presence of the iodine atom in 4-Iodophenetole makes it an excellent electrophilic coupling partner, enabling the creation of intricate molecular structures with high efficiency and selectivity. This makes it invaluable in the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals.

Quality Assurance and Supply from NINGBO INNO PHARMCHEM CO.,LTD.


At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to supplying 4-Iodophenetole of exceptional quality. Our product consistently meets rigorous enterprise standards, typically exhibiting a purity greater than 99.5%. Each batch undergoes stringent quality control assessments to ensure it aligns with specified purity levels and physical parameters, such as a confirmed melting point within the 25-28 degrees Celsius range.


As a reliable manufacturer and supplier of 4-Iodophenetole, NINGBO INNO PHARMCHEM CO.,LTD. offers flexible packaging options, including 20kg fluorinated barrels, or custom packaging solutions tailored to customer requirements. Our commitment extends to ensuring stable supply and competitive pricing for all our clients.


For those looking to buy 4-Iodophenetole or inquire about its current price, NINGBO INNO PHARMCHEM CO.,LTD. is ready to assist. Our dedicated sales team can provide detailed product specifications, safety data sheets, and information regarding purchase procedures. We invite prospective clients to reach out for a comprehensive understanding of our offerings and how we can meet your specific chemical sourcing needs.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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