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4-Methoxyphenylacetic Acid: Properties, Uses, and Sourcing Strategies

In the vast landscape of fine chemicals, certain compounds stand out for their fundamental importance and versatility. 4-Methoxyphenylacetic Acid, bearing the CAS number 104-01-8, is one such compound. This carboxylic acid derivative, characterized by its methoxy-substituted phenylacetic structure, is a pivotal intermediate in various industrial and research applications. Understanding its properties, applications, and effective sourcing strategies from manufacturers is crucial for anyone involved in chemical procurement or synthesis.

Physically, 4-Methoxyphenylacetic Acid typically presents as a white to light yellow crystalline powder or chunks. Its melting point, generally between 84-86 °C, and its solubility characteristics (e.g., 6g/L in water at 20 °C) are important parameters for handling and process design. Chemically, its pKa of 4.358 at 25 °C indicates it is a moderately acidic compound. These properties, readily available from reliable chemical data providers and manufacturers, are essential for chemists and process engineers to optimize its use in reactions.

The primary utility of 4-Methoxyphenylacetic Acid is as a key intermediate in the synthesis of pharmaceuticals and other complex organic molecules. Its structure lends itself to a variety of chemical transformations, making it a valuable building block for drug discovery and development. It has been noted for its role in synthesizing compounds with potential therapeutic applications, highlighting its significance in the pharmaceutical industry. For buyers seeking to purchase 4-methoxyphenylacetic acid, ensuring high purity is critical for these sensitive applications.

Furthermore, research has explored 4-methoxyphenylacetic acid as a potential biomarker, adding another dimension to its scientific relevance. Its presence as a metabolite in biological systems suggests ongoing investigation into its diagnostic capabilities, particularly in areas like early cancer detection. This broad spectrum of use underscores the consistent demand for this chemical intermediate.

When sourcing 4-Methoxyphenylacetic Acid, prospective buyers often look towards global manufacturers, with China being a prominent hub. The availability of this compound from Chinese suppliers offers competitive pricing and diverse supply options. When engaging with a manufacturer or supplier, it is important to consider not only the price of 4-methoxyphenylacetic acid but also their production capacity, quality assurance protocols, and logistics. Requesting detailed specifications and a quote is the standard procedure for industrial procurement.

In conclusion, 4-Methoxyphenylacetic Acid (CAS 104-01-8) is a critical intermediate with a defined set of physical and chemical properties that dictate its extensive use in pharmaceutical synthesis, organic chemistry, and research. Understanding these aspects, coupled with a strategic approach to sourcing from reliable manufacturers, is essential for any organization relying on this versatile chemical.

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