Understanding the chemical properties of key intermediates is fundamental for chemists and procurement specialists in the B2B sector. 4-Methyl-2-(trifluoromethyl)aniline, identified by its CAS number 87617-23-0, is a prime example of such a compound, extensively used in organic synthesis. As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. provides this critical intermediate, ensuring it meets the high standards required for its diverse applications.

Key Chemical Properties and Their Significance

4-Methyl-2-(trifluoromethyl)aniline is characterized by its molecular formula C8H8F3N and a molecular weight of approximately 175.15 g/mol. Its physical properties include a density of around 1.237 g/cm³ and a boiling point of approximately 199.9°C at standard atmospheric pressure. The flash point of 82.2°C indicates moderate flammability, requiring appropriate handling procedures. Crucially, its structure features an aniline ring substituted with a methyl group at the para position and a trifluoromethyl (CF3) group at the ortho position relative to the amino group. This specific arrangement of functional groups is responsible for its reactivity and utility.

The trifluoromethyl group (CF3) is strongly electron-withdrawing. This electron-withdrawing effect influences the electron density of the aromatic ring and the basicity of the amino group. Consequently, it can affect reaction rates and regioselectivity in various synthetic transformations, such as electrophilic aromatic substitution or nucleophilic reactions. The steric bulk of the CF3 group also plays a role in dictating the accessibility of neighboring reaction sites.

Versatile Applications in Organic Synthesis

The chemical reactivity of 4-Methyl-2-(trifluoromethyl)aniline makes it an indispensable intermediate in several industrial sectors. When you buy this product, you are acquiring a versatile building block for:

• Pharmaceutical Synthesis: The compound is frequently used to construct complex drug molecules. The trifluoromethyl moiety is often incorporated to enhance pharmacological properties like metabolic stability, lipophilicity, and target binding affinity. Researchers aiming to synthesize novel APIs often seek out this intermediate.
• Agrochemicals: In the development of herbicides, fungicides, and insecticides, 4-Methyl-2-(trifluoromethyl)aniline serves as a key precursor. The presence of the CF3 group can lead to enhanced biological activity and selective toxicity in crop protection agents. Procuring this from a reliable supplier ensures the efficacy of your agrochemical formulations.
• Material Science: Its unique electronic and thermal properties make it suitable for synthesizing advanced materials, including certain types of polymers and liquid crystals. This application is growing as researchers explore new fluorinated materials with tailored characteristics.

Sourcing from a Trusted Manufacturer

For businesses looking to purchase 4-Methyl-2-(trifluoromethyl)aniline, partnering with a reputable manufacturer and supplier like NINGBO INNO PHARMCHEM CO.,LTD. is paramount. We offer this intermediate with a guaranteed purity of ≥98.0%, ensuring consistency and reliability for your synthesis needs. By providing high-quality materials and dependable supply, we empower innovation across these critical industries. When you need to buy this essential chemical, rely on our expertise and commitment to quality.