4-P-Aminophenyl-1-Boc-Piperidine (CAS 170011-57-1) stands as a pivotal chemical compound in advanced organic synthesis, particularly within the pharmaceutical sector. This high-purity substance, typically presenting as a white to brown crystalline powder with a minimum purity of 97%, is defined by its molecular formula C16H24N2O2 and a molecular weight of 276.374. Its established physical properties include a boiling point of 412.7±45.0 °C at 760 mmHg and a density of 1.1±0.1 g/cm3. While its melting point is reported to be between 117-121°C, its most defining feature is the presence of a tert-butyl protecting group, which significantly enhances its chemical stability and reactivity, rendering it an exceptionally valuable asset in intricate synthetic pathways.

The primary utility of 4-P-Aminophenyl-1-Boc-Piperidine lies in its role as a versatile pharmaceutical intermediate. It is instrumental in the synthesis of a broad spectrum of novel drug candidates. Its unique structural configuration facilitates its seamless integration into complex organic molecules, thereby opening avenues for the exploration of new therapeutic strategies and offering substantial advantages in contemporary drug discovery efforts. A prominent application includes its employment in the development of analgesics and neuroactive agents, making it indispensable for research initiatives focused on neurological disorders. Furthermore, this compound is specifically utilized in the synthesis of FMS inhibitors, which are crucial for the development of treatments for chronic inflammatory conditions, such as rheumatoid arthritis. This direct contribution to enhancing patient well-being underscores its profound importance in medicinal chemistry.

Beyond its significant contributions to pharmaceutical development, 4-P-Aminophenyl-1-Boc-Piperidine exhibits utility across other vital scientific disciplines. In the field of materials science, it serves as a valuable building block for the creation of functionalized polymers and advanced materials. Its advantageous properties, including optimal solubility and reactivity, position it as a preferred choice for researchers striving to innovate in the development of composites that boast improved mechanical strength and novel functionalities. Additionally, in biochemical research, this compound is frequently employed in studies investigating receptor binding and enzyme inhibition. Such investigations are fundamental to unraveling basic biological processes and elucidating the complex interactions of pharmaceutical molecules within biological systems, thus deepening scientific understanding.

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