5-Bromo-2-chlorotoluene, identified by its CAS Number 54932-72-8, stands as a crucial intermediate in the realm of organic synthesis. This chemical compound, also known by synonyms such as 4-bromo-1-chloro-2-methylbenzene or Benzene, 4-bromo-1-chloro-2-methyl-, plays a vital role in constructing more complex molecules across various chemical industries.
As a halogenated toluene derivative, 5-Bromo-2-chlorotoluene possesses distinct chemical properties that make it highly valuable. Its molecular formula is C7H6BrCl, resulting in a molecular weight of approximately 205.480 g/mol. Physically, it typically presents as a colourless to yellow liquid. Key physical and chemical specifications include a density of around 1.5±0.1 g/cm³, a boiling point of approximately 216.9±20.0 °C at 760 mmHg, and a flash point of about 99.1±11.9 °C. The material specification ensures a high level of purity, with an assay typically ≥98.0%.
The primary application of 5-Bromo-2-chlorotoluene lies in its function as an organic synthesis intermediate. The strategically positioned bromine and chlorine atoms on the toluene ring provide reactive sites that can be utilized in a wide range of chemical transformations. These include, but are not limited to, cross-coupling reactions such as Suzuki, Heck, and Sonogashira couplings, Grignard reactions, and nucleophilic substitution reactions. These reactions are fundamental in building complex organic structures required for the synthesis of pharmaceuticals, agrochemicals, specialty chemicals, and advanced materials.
Its utility as a versatile building block allows chemists to introduce both halogen substituents and a methyl group into target molecules with precision. This enables the creation of novel compounds with desired biological activities or material properties. The reliability and reactivity profile of 5-Bromo-2-chlorotoluene contribute significantly to the efficiency and success of multi-step synthesis routes in research and industrial production.
Proper handling and storage are essential for maintaining the quality and safety of this chemical. It is recommended to store 5-Bromo-2-chlorotoluene in a cool, ventilated place, away from incompatible materials and sources of ignition, given its flash point. Standard packaging is typically in 200 kg drums, but packaging can often be customized according to specific customer requirements. Safe handling practices, including the use of appropriate personal protective equipment and working in well-ventilated areas, should always be followed.
In summary, 5-Bromo-2-chlorotoluene is an indispensable intermediate for chemists worldwide. Its unique combination of structure and reactivity facilitates the synthesis of diverse organic compounds critical to numerous industries.
For those requiring this essential chemical, finding a reputable 5-Bromo-2-chlorotoluene manufacturer is crucial to ensure consistent quality and supply reliability. Prospective buyers should seek out an established 5-Bromo-2-chlorotoluene supplier known for excellent service and technical support. Understanding the current 5-Bromo-2-chlorotoluene price is also key for effective procurement planning. Whether you need to buy 5-Bromo-2-chlorotoluene in bulk or smaller quantities for research or production, it is advisable to engage with experienced chemical suppliers offering high-purity material.
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