In the realm of synthetic organic chemistry, the precise manipulation of molecular structures is key to creating new materials and medicines. Organic intermediates, such as 5-Bromo-7-azaindole, are the cornerstones of these complex synthetic endeavors. This article provides an in-depth look at the chemical properties and diverse synthesis uses of 5-Bromo-7-azaindole (CAS 183208-35-7), guiding researchers and procurement specialists on its acquisition from reliable manufacturers.

Chemical Profile of 5-Bromo-7-azaindole

5-Bromo-7-azaindole is an organobromine compound belonging to the azaindole family. Its core structure is a fusion of a benzene ring and a pyridine ring, with a nitrogen atom at the 7-position and a bromine atom at the 5-position. The precise identification through its CAS number, 183208-35-7, ensures that researchers are acquiring the correct compound for their specific applications. Key chemical properties include:

• Molecular Formula: C7H5BrN2
• Molecular Weight: Approximately 197.03 g/mol
• Appearance: Typically a white to off-white powder.
• Solubility: Soluble in common organic solvents like DMSO, DMF, and moderately soluble in methanol and ethanol.
• Reactivity: The bromine atom at the 5-position makes it highly reactive in various palladium-catalyzed cross-coupling reactions, such as Suzuki-Miyaura, Heck, and Sonogashira couplings. The nitrogen atoms in the azaindole core also offer sites for further functionalization or coordination.

Versatile Synthesis Applications

The reactivity and structural features of 5-Bromo-7-azaindole lend themselves to a wide array of synthetic transformations, making it a sought-after intermediate for chemists worldwide. Its primary uses include:

• Synthesis of Heterocyclic Compounds: It serves as a critical building block for creating more complex heterocyclic systems found in pharmaceuticals, agrochemicals, and functional materials.
• Cross-Coupling Reactions: The presence of the bromine atom is ideal for forming new carbon-carbon or carbon-heteroatom bonds through various palladium-catalyzed reactions. This allows for the introduction of diverse substituents onto the azaindole core.
• Drug Discovery and Development: As previously noted, it is a key intermediate in the synthesis of potential drug candidates, including its role as a ZCCHC12 inhibitor. Researchers looking to buy this for drug discovery efforts rely on its consistent quality.
• Materials Science: Derivatives of 5-Bromo-7-azaindole can be incorporated into organic electronic materials, fluorescent probes, or other advanced materials due to their conjugated systems and potential for tailored photophysical properties.

Sourcing 5-Bromo-7-azaindole: The Supplier’s Role

When you need to buy 5-Bromo-7-azaindole, selecting a reputable manufacturer is crucial for ensuring product quality and reliable supply. A trusted CAS 183208-35-7 supplier will offer:

• High Purity: Typically 99% or higher, verified by analytical data.
• Consistent Batch Quality: Ensuring reproducible results in your syntheses.
• Technical Support: Providing detailed product information and assistance.
• Competitive Pricing: Offering value for investment from manufacturing hubs like China.

As a dedicated manufacturer and supplier, we specialize in providing high-quality 5-Bromo-7-azaindole. We understand the importance of precise chemical properties for successful synthesis and are committed to delivering products that meet the highest standards. For those seeking to purchase this vital organic intermediate, we offer a dependable source with competitive pricing.

In conclusion, 5-Bromo-7-azaindole, with its well-defined chemical properties and versatile synthesis applications, is an indispensable tool in modern chemistry. By sourcing this key intermediate from a reliable manufacturer, researchers and chemists can confidently advance their projects and contribute to scientific innovation.