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6-Chloro-1-hexene: A Versatile Pharmaceutical Intermediate

6-Chloro-1-hexene, identified by its CAS number 928-89-2, is a crucial chemical compound widely recognized for its significant role as a pharmaceutical intermediate. This colorless transparent liquid, with the molecular formula C6H11Cl and a molecular weight of 118.605 g/mol, is a building block in various complex organic syntheses. Its unique structure, an ω-chloro-1-alkene, provides dual functionality, making it invaluable for advanced chemical reactions.


The physical and chemical properties of 6-Chloro-1-hexene are well-defined, ensuring its consistent performance in industrial applications. It typically exhibits a density of 0.896 g/cm3 and a boiling point ranging from 135-136ºC. With a flash point of 29ºC and a refractive index of 1.438, this compound requires careful handling due to its flammable nature. Its high purity, generally maintained at ≥97.0%, is critical for its efficacy, especially in sensitive pharmaceutical processes where even minor impurities can compromise the final product's quality.


The utility of 6-Chloro-1-hexene extends across a broad spectrum of chemical transformations. As a vital pharmaceutical intermediate, it participates in reactions fundamental to drug development. For instance, it is known to react effectively with β-substituted imines in the presence of a rhodium catalyst, leading to the formation of highly valuable tri- and tetra-substituted imines. Furthermore, it undergoes efficient cross-coupling reactions, often facilitated by copper(II) chloride and 1-phenylpropyne, showcasing its versatility in carbon-carbon bond formation. This compound is also instrumental in the synthesis of specific organic structures, such as 1-(5-hexen)-2,3-dimethyl-imidazolium chloride, underscoring its importance in the creation of advanced chemical entities.


At NINGBO INNO PHARMCHEM CO.,LTD., we adhere to stringent quality control measures to ensure that our 6-Chloro-1-hexene meets the highest industry standards. Our comprehensive analysis includes rigorous assays for purity, typically achieving results of 98.3%, alongside meticulous checks for single impurities and water content, ensuring both are well within acceptable limits. This dedication to quality guarantees that our product consistently conforms to factory standards, providing reliability and consistency for our clients' critical applications.


Proper storage and handling of 6-Chloro-1-hexene are essential for maintaining its integrity and ensuring safety. It is recommended to store the product in a dry, inert atmosphere, keeping the container tightly sealed in a cool, dry place. Given its flammability, it should be stored in a designated flammables area and kept away from strong oxidizing agents. Adherence to these guidelines minimizes risks and preserves the product's quality over time.


As a leading manufacturer and supplier of specialty chemicals, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing high-quality 6-Chloro-1-hexene. Our commitment to excellence, coupled with robust manufacturing processes, positions us as a reliable partner for your chemical needs. For competitive price inquiries or to buy/purchase this essential chemical, interested parties are encouraged to contact our sales team. We ensure reliable supply and excellent customer service, supporting your advanced chemical synthesis requirements.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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