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7-Aminoindole (CAS 5192-04-1): Key Intermediate for Pharmaceutical Synthesis

7-Aminoindole (CAS 5192-04-1): A Versatile Indole Derivative for Advanced Chemical Synthesis


7-Aminoindole, identified by its Chemical Abstracts Service (CAS) number 5192-04-1, is a significant organic compound that has garnered substantial attention in various scientific and industrial domains. This indole derivative, also known by synonyms such as 1H-Indol-7-amine and (Indol-7-yl)amine, is characterized by its distinct chemical structure and multifaceted applications. Its unique properties make it an indispensable building block in the synthesis of complex molecules, particularly within the pharmaceutical and chemical research sectors.


Chemically, 7-Aminoindole possesses a molecular formula of C8H8N2 and a molecular weight of approximately 132.16 g/mol. Typically appearing as a light brown to brown solid, its physical characteristics are well-defined. It exhibits a melting point generally ranging from 94°C to 100°C, and a boiling point around 354°C at standard pressure. These thermal properties are crucial for its handling and application in diverse synthetic routes. For optimal preservation of its integrity and reactivity, 7-Aminoindole should be stored in a cool environment, specifically at temperatures between 2-8°C, and protected from light, which can degrade its sensitive chemical structure.


The utility of 7-Aminoindole extends across a broad spectrum of applications, highlighting its versatility. Primarily, it serves as a vital pharmaceutical raw intermediate, playing a crucial role in the development and synthesis of novel drug candidates. Its indole scaffold is prevalent in many biologically active compounds, making 7-Aminoindole a key starting material for creating new therapeutic agents. Beyond pharmaceuticals, it is widely utilized as an intermediate in various general synthesis materials, contributing to the creation of advanced chemical products and specialty chemicals.


Recent research has further illuminated the profound biological activities associated with 7-Aminoindole. It has been identified as a potent inhibitor of several critical enzymes and receptors, including Histone Deacetylases (HDAC), Protein Kinase C (PKC), and Aurora Kinase (ARK). These inhibitory actions underscore its potential in medicinal chemistry, particularly in areas like cancer research, where these targets are significant. Furthermore, 7-Aminoindole acts as an antagonist to Transient Receptor Potential Vanilloid 1 (TRPV1) and the mineralocorticoid receptor, expanding its therapeutic relevance. It is also recognized as a Factor Xa inhibitor, indicating its possible role in anticoagulant development. These diverse biological roles make 7-Aminoindole a compound of significant interest for ongoing drug discovery efforts.


At NINGBO INNO PHARMCHEM CO.,LTD., we are committed to providing high-quality 7-Aminoindole with a minimum purity of 97%. Our stringent quality control measures ensure that every batch meets the demanding specifications required for critical applications in pharmaceutical and advanced chemical synthesis. We understand the importance of reliable supply for research and development, as well as for industrial production. Therefore, we strive to maintain consistent product availability and deliver materials that empower our clients' innovations.


For those looking to buy 7-Aminoindole or seeking a dependable 7-Aminoindole supplier, NINGBO INNO PHARMCHEM CO.,LTD. stands as a premier choice. As an established manufacturer of 7-Aminoindole, we pride ourselves on our technical expertise and capacity to produce this compound with exceptional purity and consistency. We offer competitive 7-Aminoindole price options, tailored to meet various order quantities, from laboratory scale to bulk purchases. Our focus is on fostering long-term partnerships by ensuring prompt delivery and providing comprehensive technical support. Whether you are conducting cutting-edge research or engaging in large-scale production, consider us your trusted partner for high-grade 7-Aminoindole. We invite inquiries for detailed product specifications, availability, and to discuss your specific requirements for purchase of 7-Aminoindole, ensuring you receive the highest quality product for your needs.

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