9-Fluorenemethanol, also known by its CAS number 24324-17-2 and the alternative name 9-(Hydroxymethyl)fluorene, stands as a pivotal chemical compound in modern organic synthesis. Its unique molecular structure, characterized by a fluorene backbone with a hydroxymethyl group, imparts exceptional properties that are highly valued across various chemical and pharmaceutical applications.

This compound, with a molecular formula of C14H12O and a molecular weight of 196.24 g/mol, typically presents as a crystalline or crystalline powder, sometimes appearing in chunks. It is a solid at room temperature and possesses a distinct melting point, commonly reported between 105-107° C. These physical attributes ensure its stability and ease of handling in laboratory and industrial settings.

The primary and perhaps most significant application of 9-Fluorenemethanol lies in its function as a protecting group. It is widely employed as both a carboxy protecting group and, crucially, as a phosphate protecting group. This protective capacity is particularly indispensable in the intricate synthesis of deoxyribo-oligonucleotides. In this context, 9-Fluorenemethanol facilitates temporary modification of sensitive functional groups, preventing unwanted side reactions during multi-step synthesis. Its ability to be selectively removed under mild conditions, often via a beta-elimination mechanism, makes it an ideal choice for protecting groups where precision and integrity of the final product are paramount.

Beyond oligonucleotide synthesis, 9-Fluorenemethanol is an integral component in Fmoc (9-fluorenylmethyloxycarbonyl) chemistry, a widely adopted strategy in solid-phase peptide synthesis. The Fmoc group, derived from 9-Fluorenemethanol, offers distinct advantages over other protecting groups due to its mild deprotection conditions, which significantly reduce the risk of racemization and degradation of sensitive peptide bonds. This versatility underscores 9-Fluorenemethanol's importance not only in genomics and molecular biology research but also in the production of therapeutic peptides and proteins.

Recognizing the critical role of high-purity chemicals in sensitive syntheses, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing premium quality 9-Fluorenemethanol. Our rigorous quality control processes ensure that every batch meets stringent specifications, offering researchers and manufacturers a reliable and consistent supply for their demanding applications. The purity of 9-Fluorenemethanol directly impacts the yield and integrity of the final product, especially in pharmaceutical and biotechnological syntheses where even trace impurities can compromise efficacy and safety.

For those seeking a dependable manufacturer and supplier of high-grade 9-Fluorenemethanol, NINGBO INNO PHARMCHEM CO.,LTD. stands as a trusted partner. We offer competitive price options and flexible supply chains to meet the diverse needs of laboratories and production facilities worldwide. Whether you are looking to buy a small quantity for research or require a large-scale purchase for industrial production, our team is equipped to provide comprehensive support and superior products. We invite you to connect with us to discuss your specific requirements for 9-Fluorenemethanol (CAS 24324-17-2) and experience the dedication to quality that sets us apart.