In the evolving landscape of advanced skincare, Acetyl Tetrapeptide-9 stands out as a cutting-edge ingredient, gaining significant attention for its remarkable ability to restore skin’s youthful vitality. This synthetic signal peptide, also known by its CAS No. 928006-50-2, represents a sophisticated advancement in anti-aging science, offering a targeted approach to improving skin architecture and resilience.

Chemically defined as N-Acetyl-L-glutaminyl-L-α-aspartyl-L-valyl-L-histidine, or simply N-Acetyl-Gln-Asp-Val-His, Acetyl Tetrapeptide-9 is a precise sequence of four amino acids. Its molecular weight is 539.539 g/mol, and it typically appears as a white powder with a high purity of ≥95%. These precise chemical characteristics ensure its efficacy and stability within cosmetic formulations. Unlike many oil-soluble ingredients, Acetyl Tetrapeptide-9 is readily soluble in water, making it versatile for various skincare product types, including serums, creams, and lotions.

The primary mechanism of action for Acetyl Tetrapeptide-9 lies in its profound influence on the extracellular matrix (ECM) of the skin. It specifically targets and stimulates the synthesis of lumican, a specialized proteoglycan. Lumican plays a crucial role in organizing collagen fibers into functional, strong networks that are essential for maintaining skin smoothness and tautness. As we age, the natural production and organization of these vital components diminish, leading to visible signs of aging such as wrinkles, fine lines, and loss of firmness.

Beyond stimulating lumican, this powerful peptide has been scientifically proven to promote the increase of fibroblasts in the dermis. Fibroblasts are the cells responsible for producing collagen, elastin, and glycosaminoglycans, including hyaluronic acid. These components are fundamental to the skin’s structure, elasticity, and hydration. By boosting their natural levels, Acetyl Tetrapeptide-9 helps to counteract the age-related decline, resulting in skin that is noticeably firmer, smoother, and more resilient. The visible benefits include enhanced skin density, improved facial contour, and a significant reduction in the appearance of sagging.

Moreover, the ingredient is highly regarded for its excellent tolerability. Due to its biomimetic nature, mimicking natural skin proteins, Acetyl Tetrapeptide-9 presents minimal risk to the epidermis and is well-received by various skin types, including mature and sensitive skin. It is typically incorporated into cosmetic formulations at dosages ranging from 2% to 10%, ensuring optimal efficacy without compromising skin safety. Its application extends beyond facial care, finding utility in a range of products from eye contour treatments and moisturizers to specialized hair care formulations such as shampoos and styling foams, where it contributes to overall hair and scalp health.

For formulators and manufacturers seeking high-quality raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is a reputable manufacturer and supplier of Acetyl Tetrapeptide-9. We adhere to stringent quality control standards, ensuring that our product meets the highest specifications for purity and performance. Our Acetyl Tetrapeptide-9 is supplied as a white powder, typically packaged in 25 kg drums, with custom packaging options available to meet specific customer requirements. Proper storage in a cool, ventilated place ensures product integrity. For those looking to buy Acetyl Tetrapeptide-9 or inquire about its price, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive pricing and reliable supply chain solutions for your purchase needs, supporting the development of advanced skincare and cosmetic products worldwide.