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Acriflavine Hydrochloride: Pioneering HIF-1 Inhibition in Cancer Research

The quest for novel cancer therapies is an ongoing endeavor, with researchers constantly exploring new molecular targets and compounds. Hypoxia-inducible factor 1 (HIF-1) has emerged as a crucial transcription factor in cancer biology, responding to low oxygen conditions within tumors and facilitating their growth, angiogenesis, and resistance to treatment. Disrupting HIF-1 activity presents a promising strategy for anti-cancer drug development. In this context, Acriflavine Hydrochloride has garnered significant attention as a potent HIF-1 inhibitor, opening new avenues in advanced chemical reagents for cancer research.

Studies have compellingly shown that Acriflavine Hydrochloride operates by inhibiting the dimerization of HIF-1α, thereby preventing its functional activity. This inhibitory action leads to a cascade of anti-cancer effects, including the induction of cell death and apoptosis in various glioma cell lines. Moreover, it significantly decreases the levels of key pro-survival and pro-angiogenic proteins such as PGK1 and VEGF, both of which are critical for tumor progression. The precise mechanism by which Acriflavine Hydrochloride achieves these effects makes it a valuable compound for deeper understanding of hypoxia pathways and developing targeted therapies.

Researchers worldwide are incorporating Acriflavine Hydrochloride HIF-1 inhibitor cancer studies into their protocols, seeking to leverage its unique properties. Its efficacy has been demonstrated both in vitro and in vivo, underscoring its potential as a therapeutic agent. For research institutions and pharmaceutical companies, accessing high-purity Acriflavine Hydrochloride is essential for reliable and reproducible experimental outcomes. NINGBO INNO PHARMCHEM CO.,LTD., as a dedicated Acriflavine Hydrochloride manufacturer, provides the consistent quality required for cutting-edge cancer research.

The availability of a trusted Acriflavine Hydrochloride supplier is vital for accelerating discovery in this critical area. NINGBO INNO PHARMCHEM CO.,LTD. ensures that researchers can buy Acriflavine Hydrochloride powder of the highest grade, suitable for the rigorous demands of oncology studies. When considering the Acriflavine Hydrochloride price for bulk purchases or specific research quantities, researchers can expect competitive offerings without compromising on purity. This commitment to quality and accessibility positions NINGBO INNO PHARMCHEM CO.,LTD. as a preferred partner for those pioneering new treatments and deepening our understanding of cancer mechanisms. Investing in high-grade chemical reagents for cancer research is an investment in future health, and Acriflavine Hydrochloride from a reputable supplier like NINGBO INNO PHARMCHEM CO.,LTD. is an excellent choice.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
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