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Acrylonitrile: The Versatile Intermediate for Your Next Chemical Synthesis Project

Acrylonitrile (CAS 107-13-1) is far more than just a monomer; it is a highly reactive and versatile intermediate that plays a pivotal role in numerous organic synthesis pathways. For chemists and researchers in the pharmaceutical, agrochemical, and specialty chemical sectors, understanding its synthetic utility is key to unlocking new product development and optimizing existing processes. As a dedicated manufacturer and supplier, we provide high-purity Acrylonitrile to fuel your next breakthrough.

The nitrile group (–C≡N) in Acrylonitrile is a highly reactive functional group, readily undergoing a variety of chemical transformations. One of the most significant reactions is hydrocyanation, where the addition of hydrogen across the double bond yields propionitrile. This reaction is a fundamental step in producing various aliphatic nitriles, which can be further hydrolyzed to carboxylic acids or reduced to amines, both of which are crucial building blocks in organic chemistry.

Another key synthetic application of Acrylonitrile is in cyanoethylation reactions. In this process, Acrylonitrile reacts with protic nucleophiles such as alcohols, thiols, and amines under basic conditions. This reaction introduces a cyanoethyl group (–CH₂CH₂CN) onto the nucleophile, creating longer carbon chains with a terminal nitrile functionality. These cyanoethylated compounds are valuable intermediates for synthesizing pharmaceuticals, fragrances, and complex organic molecules. For instance, the reaction with hydrogen cyanide leads to succinonitrile, a precursor for adiponitrile, which is essential for nylon production. If you are planning such syntheses, reliably buying Acrylonitrile from a chemical manufacturer with strict quality controls is essential.

Acrylonitrile also participates in Diels-Alder reactions as a dienophile, enabling the formation of cyclic compounds. This cycloaddition chemistry is fundamental in creating complex ring systems found in many natural products and pharmaceuticals. Its ability to act as an electrophile, particularly at the beta-carbon of the vinyl group, makes it a valuable partner in Michael additions and other nucleophilic addition reactions. These pathways allow for the precise construction of carbon skeletons, a core aspect of modern synthetic organic chemistry.

Furthermore, the polymerization capabilities of Acrylonitrile, while often viewed as its primary use, also have implications for synthesis. Controlled polymerization or oligomerization can be leveraged to create specific functionalized materials or intermediates. For researchers looking to buy Acrylonitrile for their synthesis projects, understanding the available grades and the impact of stabilizers is important. We ensure our Acrylonitrile offers a high assay, minimizing interference with sensitive synthetic steps.

For any laboratory or industrial process requiring Acrylonitrile as a synthesis intermediate, sourcing from a reliable manufacturer in China is a strategic advantage. We offer competitive Acrylonitrile price points, especially for those purchasing in larger quantities for ongoing research or production. Our commitment to quality and consistent supply makes us an ideal partner for your chemical synthesis needs. Contact us today to discuss your requirements and obtain a quote for your Acrylonitrile purchase.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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