Ammonium Glycyrrhizate, identified by its Chemical Abstracts Service (CAS) number 53956-04-0, is a remarkable compound extracted from the roots of the licorice plant, Glycyrrhiza glabra. Known also as Monoammonium Glycyrrhizinate, this white needle-like crystalline or crystalline powder boasts a molecular formula of C42H65NO16 and a molecular weight of 839.96. Its unique properties make it a highly sought-after ingredient across a spectrum of global industries.

NINGBO INNO PHARMCHEM CO.,LTD. ensures the superior quality of Ammonium Glycyrrhizate, with specifications indicating an assay purity of 98.0%–102.0%. Our product adheres to stringent quality controls, including rigorous testing for impurities such as loss on drying (NMT 6.0%), water content (NMT 6.0%), and sulphated ash (NMT 0.2%). Furthermore, it meets strict limits for total heavy metals (NMT 20ppm), lead (NMT 3ppm), arsenic (NMT 1ppm), cadmium (NMT 1ppm), and mercury (NMT 0.1ppm), ensuring safety and reliability. Microbial testing also confirms the absence of harmful bacteria like E. Coli, Salmonella, Staphylococcus Aureus, and Pseudomonas Aeruginose, guaranteeing a safe and high-quality product for all applications.

The versatility of Ammonium Glycyrrhizate is evident in its wide array of applications:

In the pharmaceutical industry, Ammonium Glycyrrhizate is highly valued for its therapeutic benefits. It is widely recognized for its efficacy in relieving coughs and reducing phlegm. Moreover, its potent anti-inflammatory and antiviral properties make it a crucial component in treating various liver diseases, including chronic hepatitis. Research indicates its role in modulating inflammatory responses by inhibiting the enzyme 11β-hydroxysteroid dehydrogenase type 2 and nuclear factor-kappa B (NF-κB), key regulators of inflammation. Recent studies have also explored its potential in mitigating neuropathic pain in diabetic models, highlighting its broad pharmacological scope.

For the cosmetics and personal care sectors, Ammonium Glycyrrhizate is a prized ingredient. It functions as an effective skin-conditioning agent, helping to reduce flaking and restore suppleness to dry or damaged skin. Its soothing and anti-irritant properties are particularly beneficial for sensitive skin, alleviating redness and discomfort. Beyond its calming effects, it is also utilized for its potential skin-whitening properties by inhibiting melanin production, thus promoting a more even skin tone. Its antioxidant capabilities further protect the skin from free radical damage, contributing to anti-aging formulations. Common cosmetic products incorporating this compound include face creams, lotions, sunscreens, after-sun treatments, and oral hygiene products.

In the food and beverage industry, Ammonium Glycyrrhizate serves primarily as a flavoring agent due to its intensely sweet taste, often being significantly sweeter than sucrose. It is used to enhance the flavor profiles of beverages, seasonings, biscuits, candies, preserved fruits, and canned meats, offering a natural sweetness and distinct licorice notes.

While Ammonium Glycyrrhizate is generally regarded as safe for its intended uses, it is important for prospective buyers and manufacturers to be aware that, like many active compounds, excessive consumption or prolonged high-dose usage can lead to side effects. These may include conditions such as hypertension (high blood pressure), hypokalemia (low potassium levels), and fluid retention, primarily due to its mineralocorticoid-like effects on electrolyte balance. Therefore, adherence to recommended concentrations and professional guidance is essential for optimal and safe utilization.

As a leading manufacturer and supplier, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing Ammonium Glycyrrhizate of exceptional quality. Our rigorous manufacturing processes and comprehensive quality assurance measures ensure that every batch meets the highest industry standards. We offer competitive price and comprehensive support to our global partners. For those looking to buy or purchase this versatile compound, samples are readily available for evaluation. We welcome inquiries and are dedicated to facilitating a seamless procurement experience for all your industrial needs.