Amoxicillin, a prominent member of the aminopenicillin class, stands as one of the most widely utilized broad-spectrum β-lactam antibiotics. Manufactured by NINGBO INNO PHARMCHEM CO.,LTD., this essential pharmaceutical raw material, specifically Amoxicillin Trihydrate (CAS 61336-70-7), is presented as a high-purity white crystalline powder, typically assaying at 99% via HPLC. Its chemical characteristics, including a molecular formula of C16H19N3O5S·3H2O and a molecular weight of 419.46, underscore its precise chemical composition crucial for therapeutic efficacy.

The mechanism of action for Amoxicillin involves interfering with the synthesis of mucopeptides in the bacterial cell wall, a critical component for bacterial survival and replication. By inhibiting bacterial metabolic enzymes and triggering the activity of the bacteria's own autolysis enzymes, Amoxicillin causes bacteria to swell, deform, rupture, dissolve, and ultimately die. This potent bactericidal effect, combined with its strong ability to penetrate cell membranes, makes it highly effective against a wide range of susceptible Gram-positive and Gram-negative bacteria. Notably, Amoxicillin exhibits excellent stability under acidic conditions, boasting a gastrointestinal absorption rate of up to 90%, which is superior to some other β-lactam antibiotics like ampicillin, leading to higher concentrations in the blood and urine. Its half-life in adults is approximately 61.3 minutes, allowing for effective dosing regimens.

Amoxicillin's therapeutic applications are extensive, covering numerous bacterial infections across human and veterinary medicine. In human health, it is clinically indispensable for treating conditions such as tonsillitis, laryngitis, pneumonia, chronic bronchitis, urinary tract infections, and skin and soft tissue infections. It is also effectively used for suppurative pleurisy, liver and biliary system infections, sepsis, typhoid fever, and dysentery. Beyond these, Amoxicillin is a key component in multi-drug regimens for treating Helicobacter pylori infections and is used in the management of acute otitis media, strep throat, and even Lyme borreliosis. For high-risk individuals undergoing dental procedures, it serves as a crucial prophylactic agent against bacterial endocarditis. Furthermore, it is employed for post-exposure inhalation of anthrax to prevent disease progression.

In veterinary applications, Amoxicillin (often combined with clavulanic acid) is widely prescribed. For dogs, it effectively treats skin and soft tissue infections, including wounds, abscesses, cellulitis, and pyoderma, as well as periodontal infections. In cats, it addresses similar skin and soft tissue infections and is a primary treatment for urinary tract infections. This broad utility underscores its importance across various animal health sectors.

While generally well-tolerated, potential side effects of Amoxicillin can include nausea, vomiting, diarrhea, and skin rashes. Serious allergic reactions, though rare, necessitate immediate medical attention. It is crucial for patients to disclose any allergies, particularly to penicillins or cephalosporins, to their healthcare providers. The product should be stored at room temperature to maintain its efficacy over a two-year shelf life.

NINGBO INNO PHARMCHEM CO.,LTD. is a dedicated manufacturer and reliable supplier of high-quality Amoxicillin Trihydrate. We ensure that our product meets stringent pharmaceutical standards, providing a crucial raw material for global pharmaceutical production. For detailed price information, to buy in bulk, or to purchase specific quantities, interested parties are encouraged to contact our sales department directly. We pride ourselves on offering competitive pricing and robust supply chain solutions for your Amoxicillin needs.