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Ancitabine HCl (CAS 10212-25-6): Synthesis, Applications, and Sourcing

Ancitabine Hydrochloride (CAS 10212-25-6), commonly known as Cyclocytidine or Cyclo-C, stands as a vital pharmaceutical intermediate with significant antineoplastic properties. Its unique structure as a nucleoside analog makes it a powerful compound in the fight against certain cancers, particularly leukemia. For researchers and manufacturers looking to buy this crucial chemical, understanding its synthesis, applications, and how to secure a reliable supply is essential.

The Chemical Profile of Ancitabine Hydrochloride
Ancitabine Hydrochloride is characterized by its white to off-white powder appearance and a high purity level, typically 98% or more. Its molecular formula, C9H12ClN3O4, and molecular weight of 261.66 contribute to its specific pharmacological activity. The CAS number 10212-25-6 is the universal identifier for this compound, essential for accurate sourcing and regulatory compliance.

Synthesis and Manufacturing Insights
The synthesis of Ancitabine Hydrochloride is a multi-step process that requires precision and specialized chemical expertise. While the detailed proprietary manufacturing processes vary, the fundamental approach often involves modifying nucleoside structures to create the arabinose sugar component. For bulk purchase inquiries, understanding the manufacturing capacity of a supplier is key. Manufacturers in China are prominent in producing this compound efficiently. When you search for 'Ancitabine HCl manufacturer' or 'Ancitabine HCl wholesale', you are often looking at companies that have mastered these complex synthetic routes.

Key Applications in Medicine and Research
The primary therapeutic use of Ancitabine Hydrochloride is as an antineoplastic agent. It is particularly effective against various forms of acute leukemia and meningeal leukemia. Its incorporation into DNA and RNA during cellular replication can disrupt these vital processes, leading to the inhibition of cancer cell growth. Beyond its direct use as a chemotherapeutic component, it also finds application in the preparation of specific eye drops, demonstrating its versatility.

For R&D purposes, Ancitabine Hydrochloride serves as a valuable research chemical. Scientists investigating new anticancer drugs or mechanisms of nucleoside analog action often require this compound. Accessing 'Ancitabine HCl for research' from a reputable supplier ensures the quality needed for accurate experimental results.

Sourcing Ancitabine Hydrochloride: A Buyer's Guide
When looking to purchase Ancitabine Hydrochloride, especially in bulk quantities, identifying a trustworthy supplier is critical. Several factors should be considered:

  • Supplier Reputation: Look for manufacturers with a proven track record in producing pharmaceutical intermediates.
  • Product Quality Assurance: Always request and review the Certificate of Analysis (CoA) to confirm purity and specifications.
  • Pricing and MOQ: Inquire about the 'Ancitabine HCl price' and Minimum Order Quantity (MOQ) to ensure it aligns with your project budget and needs. Direct manufacturers often offer the best pricing.
  • Logistics and Shipping: Understand the shipping terms (FOB, CIF, etc.) and delivery times, especially when ordering from international suppliers.

Working with established chemical sourcing platforms or directly contacting manufacturers identified through searches like 'buy Ancitabine HCl CAS 10212-25-6' can streamline the procurement process. Companies like NINGBO INNO PHARMCHEM CO.,LTD. facilitate these connections, ensuring buyers can access high-quality pharmaceutical intermediates reliably.

In summary, Ancitabine Hydrochloride is a crucial compound in modern medicine and research. By understanding its synthesis, applications, and by diligently sourcing from reputable manufacturers, organizations can secure the quality and quantity required for their vital work.

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