Azelaic acid, an organic compound with the chemical formula C9H16O4, stands out as a versatile and effective ingredient in the realm of cosmetic and dermatological formulations. This saturated dicarboxylic acid naturally occurs in grains such as wheat, rye, and barley. In its purified form, it presents as a fine, white powder, making it an ideal raw material for various skincare and haircare products.

With a CAS number of 123-99-9, Azelaic acid has gained significant recognition for its multifaceted properties that address common skin concerns. Its efficacy is well-documented, particularly in the treatment of acne vulgaris, a widespread dermatological condition affecting millions globally. Azelaic acid works through several mechanisms to combat acne. Firstly, it exhibits antibacterial activity against Propionibacterium acnes and Staphylococcus epidermidis, two primary bacterial strains implicated in acne development. By inhibiting microbial protein synthesis, it reduces the bacterial load within pores, thus decreasing inflammation and preventing breakout formation.

Secondly, Azelaic acid possesses keratolytic properties. It helps to normalize keratinization, the process by which skin cells are produced and shed. Dysfunctional keratinization can lead to the formation of comedones (blackheads and whiteheads), which are precursors to inflammatory acne lesions. By reducing the production of keratin that promotes bacterial growth and pore blockage, Azelaic acid effectively prevents the formation of new acne lesions and clears existing ones. Its anti-inflammatory action further contributes to reducing the redness, swelling, and discomfort associated with inflammatory acne, making it a cornerstone in managing both comedonal and inflammatory types.

Beyond acne treatment, Azelaic acid is highly valued for its ability to address skin pigmentation issues. It is commonly used for the treatment of hyperpigmentation conditions, including melasma and post-inflammatory hyperpigmentation (PIH). These conditions are characterized by the overproduction and deposition of melanin, leading to dark spots and uneven skin tone. Azelaic acid functions as a potent tyrosinase inhibitor. Tyrosinase is a crucial enzyme involved in the biosynthesis of melanin. By inhibiting this enzyme, Azelaic acid effectively reduces melanin synthesis, leading to a gradual lightening of pigmented areas. This mechanism makes it a preferred alternative to other depigmenting agents like hydroquinone, particularly for individuals with darker skin types who may be more prone to irritation or paradoxical hyperpigmentation with certain treatments.

Furthermore, Azelaic acid has demonstrated effectiveness in managing rosacea, a chronic inflammatory skin condition characterized by facial redness, visible blood vessels, and sometimes papules and pustules. Its anti-inflammatory and antibacterial properties help to reduce the characteristic redness and inflammatory bumps associated with rosacea subtypes. The gentle nature of Azelaic acid compared to some other active ingredients makes it suitable for the sensitive skin often affected by rosacea.

Chemically, Azelaic acid is a saturated dicarboxylic acid with a molecular weight of 188.22. High-purity Azelaic acid powder, typically assaying at 99% or higher, is essential for cosmetic formulations to ensure efficacy and safety. Its off-white to white crystalline powder form makes it relatively easy to incorporate into various product bases, such as creams, gels, serums, and lotions. The standard transport package for bulk quantities is often a 25kg paper drum, while smaller amounts may be available in 1kg bags, catering to different manufacturing needs and scales.

While primarily celebrated for its skin benefits, Azelaic acid, often combined with zinc salts and vitamin B6, has also been explored for use in hair care products, particularly those aimed at addressing hair loss. Its potential role in this area is still being researched, but it highlights the diverse pharmacological activities of this compound.

The growing demand for effective yet gentle skincare ingredients has propelled Azelaic acid into the spotlight. Consumers are increasingly seeking products that deliver visible results without causing excessive irritation, making Azelaic acid an attractive option for formulators. Its natural origin from grains further enhances its appeal in the clean beauty market segment.

Manufacturers producing skincare and haircare products require a reliable supply of high-quality Azelaic acid powder. Finding a reputable Azelaic acid manufacturer is crucial for ensuring the consistency and purity of the final cosmetic product. Suppliers offering Azelaic acid powder often provide detailed Certificates of Analysis (COA) to verify the product's specifications, including assay, appearance, melting range, loss on drying, residue on ignition, heavy metals, and microbial limits. These quality control measures are vital for cosmetic ingredient sourcing.

When considering where to buy or purchase Azelaic acid powder, potential buyers should evaluate the supplier's production capacity, quality certifications (like ISO 9001), and experience. Understanding the typical price range per kilogram is also important for budgeting and cost analysis in production planning. Leading suppliers often offer competitive pricing based on order volume and market conditions. For businesses looking to develop new cosmetic lines or enhance existing ones with this powerful ingredient, securing a consistent and high-quality supply of Azelaic acid powder is a key step. Inquiry about pricing and minimum order quantities can typically be made directly with the supplier, facilitating the purchase process for bulk raw materials.