Azithromycin, identified by its CAS number 83905-01-5, stands as a pivotal second-generation macrolide antibiotic. Its unique chemical structure, derived from erythromycin but featuring a methyl-substituted nitrogen atom in its lactone ring, contributes to its enhanced pharmacokinetic profile and broad-spectrum activity. As a leading supplier of pharmaceutical raw materials, NINGBO INNO PHARMCHEM CO.,LTD. is committed to providing Azithromycin of exceptional purity, consistently exceeding 99% according to rigorous testing methods like HPLC, ensuring its suitability for pharmaceutical applications.

The mechanism of action for Azithromycin involves binding to the 23S rRNA of the 50S ribosomal subunit of susceptible microorganisms, thereby inhibiting bacterial protein synthesis. This effectively prevents bacteria from multiplying and ultimately leads to their demise, making it a highly effective agent against a wide array of bacterial infections. Its broad-spectrum nature means it targets numerous bacterial strains, offering versatility in treatment protocols where many other antibiotics might face resistance.

Azithromycin's therapeutic applications are extensive, covering both respiratory and reproductive tract infections, as well as various other systemic conditions. In respiratory care, it is widely utilized for treating community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, and acute bacterial sinusitis. It also serves as an important alternative therapy for pharyngitis and tonsillitis caused by Streptococcus pyogenes, particularly for individuals who cannot tolerate first-line treatments like penicillin. Furthermore, Azithromycin is effective against uncomplicated skin and soft tissue infections caused by common pathogens such as Staphylococcus aureus and Streptococcus agalactiae.

Its efficacy extends significantly into the field of sexually transmitted infections (STIs). Azithromycin is a cornerstone treatment for urethritis and cervicitis caused by Chlamydia trachomatis, often administered as a convenient single dose. It is also prescribed for certain cases of gonococcal urethritis and cervicitis, and for genital ulcer disease (chancroid) caused by Haemophilus ducreyi. Beyond these, Azithromycin finds utility in treating acute otitis media (ear infections), and off-label uses include Lyme disease (erythema migrans), pertussis (whooping cough), babesiosis, and Mycobacterium avium complex (MAC) disease in HIV-infected patients.

Dosage and administration protocols for Azithromycin vary depending on the specific infection and patient age. It is available in various forms including capsules, tablets, oral suspension, and for intravenous administration in hospital settings. A key advantage for many patients is its typically shorter course of treatment, often ranging from three to five days for common infections, and in some cases, a single high dose suffices. Patients are advised to complete the full prescribed course, even if symptoms improve, to prevent resistance development and ensure complete eradication of the infection.

While generally well-tolerated, Azithromycin can cause side effects. Common ones include gastrointestinal disturbances like diarrhea, nausea, abdominal pain, and vomiting. More serious, albeit rare, side effects can include allergic reactions (such as angioedema and anaphylaxis), hepatotoxicity (liver problems, which can be severe), and prolongation of the QT interval, a heart rhythm abnormality that can be fatal. It is crucial for healthcare professionals to assess patient medical history, including any pre-existing heart conditions or liver disease, and monitor for potential drug interactions, especially with antacids containing aluminum or magnesium, and certain anticoagulants. NINGBO INNO PHARMCHEM CO.,LTD. emphasizes that all pharmaceutical products, including Azithromycin, should be used under strict medical supervision, adhering to prescribed dosages and guidelines.

For those seeking to buy Azithromycin of the highest pharmaceutical grade, NINGBO INNO PHARMCHEM CO.,LTD. stands as a reliable Azithromycin manufacturer and supplier. We pride ourselves on maintaining stringent quality control processes to ensure every batch of Azithromycin CAS 83905-01-5 meets global pharmaceutical standards. Whether you are looking for bulk quantities or need a consistent supply, we offer competitive Azithromycin price for your purchase, ensuring both quality and efficiency in our supply chain for pharmaceutical companies and distributors worldwide.