Custom Manufacturing, Project Outsourcing, your Trusted Partner from China
In the ongoing battle against bacterial infections, the demand for effective and reliable antibiotic raw materials is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is at the forefront of this effort, offering high-grade Aztreonam Sterile Active Pharmaceutical Ingredient (API). This powerful monobactam antibiotic represents a critical tool for healthcare providers in treating severe infections caused by gram-negative bacteria.
Originally isolated from Chromobacterium violaceum, Aztreonam is a synthetic bactericidal antibiotic with a unique molecular structure. Unlike many other β-lactam antibiotics, such as penicillins and cephalosporins, Aztreonam is a monobactam, meaning its β-lactam ring is not fused to another ring. This structural distinction is key to its safety and efficacy profile.
The primary mechanism of action for Aztreonam is the inhibition of bacterial cell wall synthesis. It exhibits a high affinity for Penicillin-Binding Protein 3 (PBP3), an essential enzyme for gram-negative bacteria. By binding to and inactivating PBP3, Aztreonam disrupts the final step of peptidoglycan synthesis, which compromises the structural integrity of the bacterial cell wall. This leads to cell lysis and ultimately, the death of the pathogen.
Key Advantages and Applications
One of the most significant advantages of Aztreonam is its focused spectrum of activity. It is potent against a wide range of aerobic gram-negative pathogens, including:
This specificity makes it an excellent choice for targeted therapy. Furthermore, Aztreonam demonstrates remarkable stability in the presence of β-lactamases, which are enzymes produced by many resistant bacteria to inactivate conventional antibiotics. This resistance to enzymatic degradation allows it to remain effective where other antibiotics might fail.
Clinically, Aztreonam is used to treat a variety of serious infections, including lower respiratory tract infections, urinary tract infections (UTIs), septicemia, and skin and intra-abdominal infections. A major benefit is its low rate of cross-reactivity with other β-lactam antibiotics. This makes it a valuable alternative for patients with known allergies to penicillins or cephalosporins.
Commitment to Quality
For pharmaceutical formulation, the quality of the API is non-negotiable. At NINGBO INNO PHARMCHEM CO.,LTD., we produce Aztreonam Sterile API under stringent Good Manufacturing Practices (GMP). Our commitment ensures a product with high purity, consistency, and safety, meeting the rigorous demands of the global pharmaceutical industry.
Sourcing this critical raw material requires a partnership with a dependable manufacturer and supplier. When looking to purchase high-quality Aztreonam, it is essential to consider the provider's reputation for quality and reliability. We offer a competitive price for our premium-grade Aztreonam Sterile API, enabling our partners to develop effective and safe final drug products. For those seeking to buy this essential antibiotic powder, trusting an experienced producer is the first step toward clinical success.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
