Benzyl Chloride (CAS 100-44-7), also known as (chloromethyl)benzene or α-chlorotoluene, stands as a highly significant organic compound and a versatile chemical intermediate. It presents as a colorless to pale yellow liquid, recognizable by its characteristic pungent and aromatic odor. Structurally, it is a halogenated derivative of toluene, featuring a benzene ring with a chloromethyl group attached (C6H5CH2Cl). Its molecular weight is approximately 126.59 g/mol. The inherent reactivity of benzyl chloride, primarily due to the chlorine atom, makes it indispensable in various industrial chemical processes, serving as a fundamental building block for numerous complex molecules.

Understanding the properties of Benzyl Chloride is crucial for its safe and effective handling. It fumes in moist air and can be irritating to mucous membranes and eyes, acting as a powerful lachrymator. While sparingly soluble in water (e.g., 0.49 g/L at 20 °C), it is freely miscible with a wide array of organic solvents, including chloroform, acetone, ethanol, diethyl ether, and acetic acid esters. Key physical parameters include a boiling point around 179-197 °C, a flash point of 67 °C, and a density of approximately 1.1 g/cm3. Chemically, Benzyl Chloride is highly reactive, undergoing nucleophilic substitution reactions. It can hydrolyze to benzyl alcohol, especially in the presence of alkali. A critical consideration for storage and handling is its tendency to undergo rapid condensation polymerization when exposed to metallic ions such as iron, tin, zinc, copper, aluminum, and magnesium, a process that releases heat and hydrogen chloride gas. For this reason, inhibitors are often added during storage.

The versatility of Benzyl Chloride in organic synthesis is unparalleled. It serves as a crucial precursor for introducing the benzyl group into a multitude of molecules. This includes the synthesis of important compounds like benzylamines (via reaction with ammonia or primary amines), benzyl ethers (from alcohols or phenols), and benzyl esters (from carboxylic acids). In the pharmaceutical industry, Benzyl Chloride is an indispensable intermediate. It is widely employed in the production of various active pharmaceutical ingredients (APIs) and intermediates for drugs such as certain antidepressants, local anesthetics, penicillin, pseudoephedrine, and various cardiovascular and anti-inflammatory medications. Its role extends to providing foundational building blocks for a wide range of therapeutic agents, making it a critical component in drug manufacturing.

Beyond pharmaceuticals, Benzyl Chloride's applications span numerous sectors. In the fragrance and flavor industry, it is a key ingredient for manufacturing aromatic compounds, including benzyl acetate, a common fragrance component known for its jasmine-like scent. It also finds use in dyes and pigments, particularly in the synthesis of azo dyes, widely utilized in textile dyeing. The agrochemical sector benefits significantly from Benzyl Chloride, as it is a vital intermediate in the production of herbicides, insecticides, and fungicides, essential for crop protection and modern agriculture. Furthermore, it is integral to the polymer industry, used in the synthesis of plasticizers and resins like polystyrene, acrylics, and polyvinyl chloride (PVC), enhancing their flexibility and durability. Its utility also extends to the production of surface-active agents (surfactants), such as quaternary ammonium compounds, which are critical components in detergents, fabric softeners, and biocides used in oil drilling. Other applications include its use as a solvent, a photographic developer, and a gum inhibitor in gasoline.

Given the broad and critical applications of Benzyl Chloride, securing a reliable manufacturer and supplier of high-quality material is paramount. NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing superior Benzyl Chloride that meets stringent industry standards for purity, often exceeding 99.5%. Our commitment to quality assurance ensures that our Benzyl Chloride performs consistently in various advanced chemical syntheses and industrial applications. We understand the diverse needs of our global clientele, from large-scale industrial operations to specialized research and development initiatives. For those looking to buy or purchase Benzyl Chloride, NINGBO INNO PHARMCHEM CO.,LTD. offers competitive price options and robust supply chain solutions. We invite inquiries from potential partners seeking a dependable supplier for their Benzyl Chloride requirements, ensuring seamless procurement and high-performance products.