In the intricate world of organic synthesis, the availability of high-quality intermediates is paramount to successful research and manufacturing. Bis(4-nitrophenyl) carbonate, identified by its CAS number 5070-13-3, is one such critical intermediate that empowers chemists across various disciplines. This article provides a focused look at its chemical properties, diverse applications, and the advantages of sourcing this compound from China.

Chemical Profile and Properties of Bis(4-nitrophenyl) Carbonate

Bis(4-nitrophenyl) carbonate typically presents as a white to pale yellow or beige powder. Its molecular formula is C13H8N2O7, with a molecular weight of 304.21 g/mol. Key properties include a melting point of 136-139 °C, indicating a stable solid form under typical laboratory conditions. It demonstrates solubility in organic solvents like chloroform and tetrahydrofuran, which are common in synthesis protocols. As a chemical reagent, its purity is a critical factor, with suppliers often offering grades above 98% or 99% to meet the demands of precision chemistry.

Diverse Applications in Chemical Synthesis

The primary utility of Bis(4-nitrophenyl) carbonate lies in its reactivity as a coupling reagent. It is widely employed in:

• Peptide Synthesis: As an efficient coupling agent, it facilitates the formation of amide bonds, a cornerstone of peptide chain elongation.
• Carbamate Formation: It is a key reagent for synthesizing carbamate linkages, including its use in preparing carbamate-linked cytosines.
• Ester and Urea Synthesis: It serves as a precursor for both symmetrical and unsymmetrical urea derivatives and 4-nitrophenyl esters, broadening its synthetic scope.

These applications highlight its importance in areas ranging from medicinal chemistry and drug discovery to materials science.

Strategic Sourcing from China Manufacturers

For procurement managers and R&D scientists seeking Bis(4-nitrophenyl) carbonate, sourcing from Chinese manufacturers offers significant benefits. China has emerged as a global hub for fine chemical production, offering competitive pricing, large-scale manufacturing capabilities, and a wide array of high-purity products. When you choose to buy from a reputable Chinese supplier, you gain access to cost-effective materials without compromising on quality. It is advisable to seek suppliers who provide detailed product specifications and certificates of analysis to ensure product integrity.

Conclusion

Bis(4-nitrophenyl) carbonate (CAS 5070-13-3) is a versatile and crucial intermediate for chemists engaged in peptide synthesis, carbamate chemistry, and various other organic transformations. Its availability at high purity from Chinese manufacturers makes it an economically sound choice for both research and industrial production. We invite you to contact us to purchase Bis(4-nitrophenyl) carbonate and to benefit from our reliable supply chain and competitive pricing.