In the complex landscape of pharmaceutical manufacturing, the quality and reliability of chemical intermediates are of paramount importance. Bivalirudin, a synthetic peptide identified by its CAS number 128270-60-0, is a highly sought-after pharmaceutical intermediate due to its potent anticoagulant properties as a direct thrombin inhibitor (DTI). As a leading Bivalirudin manufacturer in China, we are dedicated to supplying this critical compound to the global pharmaceutical industry with exceptional purity and consistency.
What is Bivalirudin?
Bivalirudin is a synthetic analog of hirudin, a natural anticoagulant found in the saliva of medicinal leeches. It is a 20-amino acid peptide that directly inhibits thrombin, a key enzyme in the blood clotting cascade. Its mechanism involves binding to both the active site and the exosite of thrombin, rendering it inactive. This direct inhibition is reversible, contributing to its favorable safety profile, particularly in terms of reduced bleeding risk compared to other anticoagulants like heparin. Typically appearing as a white powder, Bivalirudin is characterized by its high purity, often exceeding 99.5%, making it ideal for pharmaceutical formulations.
Key Applications in the Pharmaceutical Industry
The primary therapeutic application for Bivalirudin is as an anticoagulant in cardiovascular medicine, especially during Percutaneous Coronary Intervention (PCI). It is used in patients undergoing procedures for unstable angina, non-ST-segment elevation myocardial infarction (NSTEMI), and ST-segment elevation myocardial infarction (STEMI). Its ability to prevent thrombus formation while minimizing adverse bleeding events makes it a preferred choice for clinicians. Beyond direct therapeutic use, Bivalirudin also serves as a vital intermediate in the research and development of new anticoagulation strategies and related pharmaceutical products.
Why Choose a China Manufacturer for Bivalirudin?
For pharmaceutical companies, sourcing critical intermediates like Bivalirudin requires careful consideration of suppliers. China has emerged as a global leader in the production of fine chemicals and pharmaceutical intermediates, offering competitive pricing and robust manufacturing capabilities. When you choose to buy Bivalirudin CAS 128270-60-0 from a reputable China manufacturer, you gain access to:
Conclusion
Bivalirudin (CAS 128270-60-0) is a critical component in modern cardiovascular medicine and a valuable pharmaceutical intermediate. By selecting a trusted Bivalirudin supplier in China, you can ensure the quality, availability, and cost-effectiveness necessary for successful pharmaceutical development and manufacturing. We are committed to being your premier partner for high-purity Bivalirudin, contributing to advancements in cardiovascular health.
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to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.