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Bivalirudin Trifluoroacetate: Understanding its Chemical Profile

In the realm of pharmaceutical chemistry, understanding the precise chemical profile of a compound is fundamental to its successful application. Bivalirudin Trifluoroacetate, a synthetic peptide renowned for its direct thrombin inhibitory properties, is one such compound that demands detailed attention to its chemical characteristics. As a key research chemical and pharmaceutical intermediate, its molecular structure, purity, and physical form are critical parameters for researchers and manufacturers.

The chemical identity of Bivalirudin Trifluoroacetate is formally defined by its CAS number: 128270-60-0. This unique identifier is crucial for accurate sourcing and regulatory compliance. Its molecular formula, C98H138N24O33·xC2HF3O2, provides insight into its complex peptide structure, which includes the trifluoroacetate salt form. This salt form often contributes to enhanced solubility and stability, making it more amenable to formulation and handling in laboratory settings.

Physically, Bivalirudin Trifluoroacetate is typically characterized as a white lyophilized powder. Lyophilization, or freeze-drying, is a process that removes water, yielding a stable, easily reconstitutable powder. This form is preferred for many active pharmaceutical ingredients (APIs) and research chemicals, as it preserves the compound's integrity and extends its shelf life.

For researchers and formulators, purity is a non-negotiable aspect. Reputable manufacturers and suppliers will specify the purity of Bivalirudin Trifluoroacetate, commonly stating it as ≥98% (HPLC). High-Performance Liquid Chromatography (HPLC) is a standard analytical technique used to determine the purity of chemical compounds, ensuring that the active ingredient is present in the desired concentration and free from significant impurities.

The applications of Bivalirudin Trifluoroacetate are primarily centered around its function as an anticoagulant. It works by specifically and reversibly inhibiting thrombin, a crucial enzyme in the blood clotting cascade. This makes it invaluable in medical procedures that require precise control over blood coagulation, such as percutaneous coronary interventions (PCI), and as an alternative in cases of heparin-induced thrombocytopenia (HIT).

Procuring Bivalirudin Trifluoroacetate from a reliable supplier guarantees that these critical chemical properties are consistently met. Whether for use in drug discovery, formulation development, or specialized research, understanding these chemical specifications ensures that the product will perform as expected. As a leading manufacturer, we pride ourselves on providing Bivalirudin Trifluoroacetate that adheres to the highest quality standards, backed by comprehensive technical data.

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