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Boc-L-Methionine (2488-15-5): A Key Amino Acid for Research

For researchers pushing the boundaries of scientific discovery, the availability of high-quality chemical reagents is non-negotiable. Boc-L-Methionine (CAS 2488-15-5) stands out as a crucial amino acid derivative, playing a pivotal role in various research disciplines, most notably in peptide synthesis, proteomics, and pharmaceutical development.

At its heart, Boc-L-Methionine is L-Methionine equipped with a tert-butoxycarbonyl (Boc) protecting group. This protection is not merely a chemical curiosity; it is fundamental to its utility. In the complex, step-by-step process of peptide synthesis, the Boc group shields the reactive amino terminus of methionine, allowing for precise, controlled elongation of the peptide chain. This ensures that the methionine residue is incorporated exactly where it is needed, preventing cross-reactions and ensuring the integrity of the synthesized peptide. Researchers often look for its characteristic white powder appearance and a melting point within the range of 47-53°C as indicators of high purity.

The applications of Boc-L-Methionine extend significantly into the field of proteomics. As researchers aim to understand the complex roles of proteins in biological systems, the ability to precisely modify or synthesize peptides is invaluable. Boc-L-Methionine serves as a key reagent in these endeavors, enabling the study of methionine's involvement in protein function, post-translational modifications, and protein degradation pathways. Its use in pharmaceutical research is also substantial, acting as a critical intermediate in the development of new drug candidates and peptide-based therapeutics.

When seeking to purchase Boc-L-Methionine, the emphasis is invariably on quality and reliability. Purity levels, often specified as u226598% by HPLC, are a primary concern for researchers. Many academic institutions and R&D departments source this compound from experienced chemical manufacturers, with China being a prominent region for production of such fine chemicals. Buyers often seek competitive pricing for bulk orders and may request free samples to verify the product's suitability for their specific research protocols. Understanding the CAS number 2488-15-5 is essential for accurate identification and procurement.

In conclusion, Boc-L-Methionine (CAS 2488-15-5) is far more than just a protected amino acid; it is an enabling tool for scientific advancement. Its critical role in peptide synthesis, proteomics research, and drug discovery underscores its importance. For any laboratory or manufacturing facility engaged in these fields, securing a consistent and high-quality supply of Boc-L-Methionine from a trusted supplier is a fundamental step towards achieving research goals and driving innovation.

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