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In the intricate landscape of chemical synthesis, particularly for pharmaceutical applications, access to high-quality, precisely engineered intermediates is non-negotiable. Boc-Phe(3,5-DiF)-OH, identified by CAS number 205445-52-9, is one such compound that serves as a crucial building block. This article aims to shed light on its properties, applications, and the advantages of sourcing it from reputable manufacturers, providing essential information for those seeking to buy this chemical.
Understanding Boc-Phe(3,5-DiF)-OH
Boc-Phe(3,5-DiF)-OH, or N-Boc-3,5-difluoro-L-phenylalanine, is a derivative of the amino acid phenylalanine. Its chemical structure is characterized by the presence of a tert-butoxycarbonyl (Boc) protecting group on the amine nitrogen and two fluorine atoms substituted at the 3 and 5 positions on the phenyl ring. The molecular formula is C14H17F2NO4, with a molecular weight of approximately 301.29 g/mol. Typically, it is supplied as a white solid, with a melting point of around 115°C, indicating its stable solid form under standard conditions.
The Boc protecting group is widely used in peptide synthesis and organic chemistry because it is stable under many reaction conditions but can be readily removed under acidic conditions. The difluoro substitution on the aromatic ring is particularly significant, as fluorine incorporation can confer desirable properties such as increased metabolic stability, altered binding affinities, and modified lipophilicity to the final synthesized molecules. This makes Boc-Phe(3,5-DiF)-OH a valuable component for drug discovery and development.
Applications and Market Sourcing
The primary application of Boc-Phe(3,5-DiF)-OH is as a pharmaceutical intermediate. It is instrumental in the synthesis of:
For organizations looking to buy Boc-Phe(3,5-DiF)-OH, sourcing from manufacturers who can guarantee high purity (e.g., ≥99.0%) and consistent batch quality is vital. Many leading chemical manufacturers are based in China, offering competitive pricing and efficient global distribution. When you plan to buy, inquire about product availability, lead times, and request a formal quotation from potential suppliers. Engaging with experienced manufacturers ensures you obtain this crucial intermediate reliably for your synthesis needs.
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