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Boronic Acids in Pharma: Why 3-Hydroxyphenylboronic Acid is a Key Intermediate

In the intricate world of pharmaceutical synthesis, the availability of high-quality building blocks is paramount. Among these essential compounds, boronic acids have emerged as indispensable tools, particularly for their role in catalyzed cross-coupling reactions. One such critical intermediate is 3-Hydroxyphenylboronic Acid (CAS: 87199-18-6). For procurement managers and R&D scientists seeking reliable sources, understanding its applications and where to buy it is key.

3-Hydroxyphenylboronic Acid, often supplied as a white crystalline powder, is renowned for its utility in forming new carbon-carbon bonds. Its primary application lies in the Suzuki-Miyaura cross-coupling reaction, a Nobel Prize-winning methodology widely adopted in the pharmaceutical industry. This reaction allows for the efficient synthesis of biaryl compounds, which are core structures in numerous blockbuster drugs.

As a leading manufacturer and supplier in China, we understand the demand for consistent purity and reliable availability of this pharmaceutical intermediate. Our 3-Hydroxyphenylboronic Acid, with an assay of ≥98.0% and low water content (≤0.50%), is produced under stringent quality controls. This ensures that researchers and production facilities can depend on its performance for sensitive synthetic pathways.

The versatility of 3-Hydroxyphenylboronic Acid extends beyond traditional Suzuki couplings. It serves as a fundamental building block in the synthesis of various Active Pharmaceutical Ingredients (APIs) and complex organic molecules. Its unique phenolic hydroxyl group and boronic acid moiety allow for diverse derivatization, enabling the creation of novel drug candidates with tailored therapeutic properties.

For businesses looking to secure a stable supply chain, partnering with a reputable manufacturer is crucial. We offer competitive prices for bulk quantities of CAS 87199-18-6, ensuring cost-effectiveness without compromising on quality. Our commitment is to provide the global pharmaceutical industry with an accessible and dependable source of this vital chemical intermediate. When you need to purchase this compound, consider the benefits of sourcing from a dedicated Chinese supplier focused on quality and service.

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NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

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2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

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  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

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