20 YEARS OF PROFESSIONAL & DEDICATED SERVICE TO GLOBAL CUSTOMERS

Custom Manufacturing, Project Outsourcing, your Trusted Partner from China

Bortezomib Intermediate: Sourcing High-Quality (1S,2S,3R,5S)-(+)-2,3-Pinanediol

For pharmaceutical manufacturers, the consistent supply of high-quality intermediates is the bedrock of successful drug production. (1S,2S,3R,5S)-(+)-2,3-Pinanediol, identified by its CAS number 18680-27-8, is a prime example of such a critical raw material, renowned for its role as a key intermediate in the synthesis of Bortezomib. Procurement managers and R&D chemists engaged in the production of this vital anti-cancer drug need to ensure they are sourcing from reliable, quality-focused manufacturers.

The Critical Role in Bortezomib Synthesis

Bortezomib, a proteasome inhibitor, is a cornerstone therapy for multiple myeloma and mantle cell lymphoma. The synthesis of Bortezomib is a multi-step process, and the stereochemical integrity of each intermediate is crucial for the final product's efficacy and safety. (1S,2S,3R,5S)-(+)-2,3-Pinanediol, a chiral bicyclic diol typically supplied as a white powder with a purity of ≥99.0%, is indispensable in one of the key stages of Bortezomib synthesis. Its specific configuration dictates the stereochemistry of subsequent steps, directly impacting the yield and purity of the final active pharmaceutical ingredient (API).

Therefore, when procuring this compound, terms like 'buy (1S,2S,3R,5S)-(+)-2,3-Pinanediol for Bortezomib production' are common search queries among pharmaceutical buyers. The emphasis is always on high chemical purity and specific enantiomeric purity, backed by robust documentation.

What Pharmaceutical Manufacturers Look For in Suppliers

For procurement managers in the pharmaceutical industry, selecting a supplier for critical intermediates like (1S,2S,3R,5S)-(+)-2,3-Pinanediol involves a rigorous evaluation process. Key considerations include:

  • Quality Assurance: Suppliers must provide detailed Certificates of Analysis (CoA) confirming purity (≥99.0%), stereochemical integrity, and other relevant specifications. Adherence to GMP standards or equivalent quality management systems is highly valued.
  • Supply Chain Reliability: A consistent and stable supply chain is vital to avoid production disruptions. Manufacturers with significant production capacity and a proven track record of on-time delivery are preferred.
  • Regulatory Compliance: Suppliers must be able to provide necessary documentation for regulatory submissions and compliance, such as Safety Data Sheets (SDS) and traceability records.
  • Technical Support: Access to technical expertise regarding product handling, storage, and application can be beneficial for process optimization.
  • Competitive Pricing: While quality is paramount, competitive pricing for bulk orders of CAS 18680-27-8 is also a significant factor. Procurement teams often solicit 'bulk quotes' from multiple reputable manufacturers.

China is a leading global supplier of pharmaceutical intermediates, and many manufacturers there specialize in chiral compounds. By partnering with these established entities, pharmaceutical companies can secure a dependable source of (1S,2S,3R,5S)-(+)-2,3-Pinanediol, ensuring their Bortezomib production remains efficient and compliant.

In conclusion, (1S,2S,3R,5S)-(+)-2,3-Pinanediol is more than just a chemical; it is a critical enabler for producing life-saving medication. For pharmaceutical manufacturers, diligently sourcing this intermediate from trusted, quality-focused suppliers is a strategic imperative.

Manufacturing Facilities

NINGBO INNO PHARMCHEM CO.,LTD. was established in 2007. It is committed to the R&D, production and sales of raw materials, pharmaceutical intermediates and fine chemicals. We striving to create a high-efficiency and high-quality integrated chemical service platform to better serve domestic and foreign customers.

Professional Export Experience

to Global Customers

WHY CHOSE US?

1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;

2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;

3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).

FAQ

  • A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.

  • A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.

  • A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.

CONTACT US
Should you need to contact us; you may call during regular business hours, Monday through Friday, 8am – 6 pm.
NINGBO INNO PHARMCHEM CO.,LTD.
Address: No.163 Ruiqing Rd.,Ningbo 315000 China
Phone: 86-574-87319282
Fax: 86-574-27912196
SEND US AN EMAIL

NAME*

EMAIL*

COMPANY

COUNTRY*

MESSAGE*

Previous: The Growing Demand for (1S,2S,3R,5S)-(+)-2,3-Pinanediol in Specialty Chemicals

Next: Sourcing High-Purity (R)-3-Boc-Aminopiperidine: A Guide for Pharma Buyers

All Rights Reserved