For professionals in chemistry, biology, and clinical diagnostics, understanding the specific properties and applications of key reagents is fundamental to successful research and analysis. Bromocresol Green (BCG), identified by its CAS number 76-60-8, is a prime example of such a vital chemical. As a dedicated supplier, we aim to provide clear insights into what makes BCG an indispensable laboratory component and how its characteristics benefit scientific endeavors.

The Chemical Profile of Bromocresol Green
Bromocresol Green is a triarylmethane dye belonging to the sulfonephthalein family. Its molecular formula is C21H14Br4O5S, with a molecular weight of approximately 698.01 g/mol. Typically supplied as a yellow crystal, it exhibits solubility in alcohol and ether, with limited solubility in water. Its chemical structure contributes to its well-defined pH-sensitive behavior, making it a reliable indicator for those looking to buy consistent quality.

Understanding the pH Indicator Functionality
The defining characteristic of Bromocresol Green is its role as a pH indicator. It undergoes a distinct color change within a specific pH range:

• Below pH 3.8: Yellow
• Between pH 3.8 and 5.4: Green (transition phase)
• Above pH 5.4: Blue

This sharp transition makes it an excellent choice for monitoring neutralizations and titrations where the equivalence point falls within this range. For researchers seeking to buy a predictable and accurate indicator, BCG is a standard. Manufacturers ensure these specifications are met to guarantee reliable performance.

Key Laboratory Applications
The versatility of Bromocresol Green extends far beyond simple pH indication:

• Acid-Base Titrations: Its sensitivity makes it ideal for titrations requiring precise endpoint detection, ensuring accurate quantitative analysis.
• Serum Albumin Determination: In clinical laboratories, BCG is crucial for quantifying serum albumin, a key biomarker for liver and kidney function. The dye's specific binding to albumin allows for colorimetric quantification, a procedure where consistent purity of the BCG reagent is essential.
• Thin-Layer Chromatography (TLC): BCG can be used as a visualization agent for acidic compounds on TLC plates, aiding in the identification of separated substances.
• Electrophoresis: It functions as a tracking dye in gel electrophoresis, allowing scientists to monitor the migration of biomolecules.
• Buffer Preparation: Assisting in the preparation and verification of buffer solutions for various experimental setups.

Ensuring Quality and Availability
When procuring Bromocresol Green, it is vital to partner with a reputable chemical supplier. Factors such as assay percentage (typically ≥98.5%), appearance, and adherence to standards like HG/T4017-2008 are indicators of quality. We, as a dedicated manufacturer and supplier in China, are committed to providing BCG that meets these rigorous standards, ensuring reliable supply and competitive pricing for laboratories globally. When you decide to buy, consider our commitment to quality assurance.

Conclusion
Bromocresol Green is a fundamental analytical tool, offering precision and versatility in various laboratory settings. Its well-defined properties, from its color transition to its application in diagnostics, make it a cornerstone reagent. Understanding its specifications and sourcing from reliable manufacturers ensures that your laboratory operations benefit from its full potential. We invite you to explore our high-quality Bromocresol Green offerings.