3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one (CAS 545445-44-1) stands as a vital organic compound with significant applications, particularly within the pharmaceutical industry. Known also by its synonyms such as 5,6-Dihydro-3-(4-morpholinyl)-1-[4-(2-oxo-1-piperidinyl)phenyl]-2(1H)-pyridinone, this chemical entity is a cornerstone intermediate in the synthesis of Apixaban, a widely recognized anticoagulant. Its precise molecular structure, with a formula of C20H25N3O3 and a molecular weight of 355.43100, ensures its distinct chemical reactivity and utility in complex synthetic pathways.

The physical and chemical properties of this compound are well-defined, contributing to its reliability in various chemical processes. It typically presents as a light beige solid, a characteristic appearance that aids in initial identification. With a melting point approximately at 199ºC, and a predicted boiling point around 624.979ºC, it exhibits thermal stability crucial for its handling and reactions. The density is recorded at 1.267, further detailing its physical characteristics. Its low solubility in common solvents like chloroform and methanol necessitates specific considerations for formulation and processing, while its predicted pKa of 3.25±0.20 hints at its acidic/basic properties under various conditions.

The primary application of 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one is its indispensable role as an intermediate in the production of Apixaban. Apixaban is a crucial active pharmaceutical ingredient (API) used globally as an oral anticoagulant, prescribed to prevent blood clots and reduce the risk of stroke in patients with atrial fibrillation, as well as for preventing deep vein thrombosis and pulmonary embolism. The consistent quality and purity of intermediates like CAS 545445-44-1 are paramount to ensuring the efficacy and safety of the final drug product. Therefore, manufacturers of such critical pharmaceutical raw materials adhere to stringent quality control standards, ensuring a minimum purity of ≥98.0% for this compound.

For researchers and pharmaceutical developers, sourcing high-quality 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one is paramount. This compound is instrumental in laboratory research and development for optimizing synthesis routes and exploring new applications within pharmaceutical chemistry. Its role as an Apixaban intermediate highlights its importance in the broader therapeutic landscape, supporting the availability of essential medications. The material is typically packaged in 25 kg drums, though custom packaging solutions can be arranged to meet specific customer requirements. Proper storage in a cool, ventilated place is recommended to maintain its integrity and extend shelf life, preserving its quality for sensitive pharmaceutical synthesis.

As a leading supplier and manufacturer of fine chemicals and pharmaceutical intermediates, NINGBO INNO PHARMCHEM CO.,LTD. is dedicated to providing premium-grade 3-Morpholino-1-(4-(2-oxopiperidin-1-yl)phenyl)-5,6-dihydropyridin-2(1H)-one. We understand the critical demand for reliable chemical supply chain management in the pharmaceutical industry. Our commitment to quality ensures that every batch meets rigorous specifications, making us a trusted partner for your production needs. For competitive price information, to buy this essential Apixaban intermediate, or to inquire about bulk purchase options, please reach out to our sales team. We strive to be your preferred manufacturer and supplier for this key compound, offering tailored solutions and dependable logistics to facilitate your research and development or large-scale production requirements.