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Catalytic cross-coupling reactions have revolutionized organic synthesis, providing efficient and selective methods for forming carbon-carbon and carbon-heteroatom bonds. Among the various organohalides employed in these transformations, iodo-aromatic compounds are particularly valuable due to the relatively weak carbon-iodine bond, which facilitates oxidative addition to catalytic metal centers. For synthetic chemists, readily available and high-purity iodo-aromatic intermediates are essential for accessing complex molecular structures.
NINGBO INNO PHARMCHEM CO.,LTD. plays a vital role in enabling these advanced synthetic strategies by supplying key intermediates such as 2-Iodo-4-(trifluoromethyl)benzoic acid (CAS: 54507-44-7). Our commitment to quality, with a guaranteed purity of ≥97%, ensures that this building block performs reliably in demanding catalytic processes. As a leading manufacturer and supplier in China, we provide the chemical foundation for innovation across pharmaceuticals, agrochemicals, and materials science.
The utility of 2-Iodo-4-(trifluoromethyl)benzoic acid in cross-coupling is multifaceted. The iodine atom readily engages in reactions like the Suzuki-Miyaura coupling (forming C-C bonds with boronic acids), Sonogashira coupling (with terminal alkynes), and Heck reaction (with alkenes). These methods are indispensable for constructing the carbon frameworks of many biologically active molecules and functional materials. The presence of the trifluoromethyl group alongside the iodine atom further expands the synthetic possibilities, allowing for the introduction of electron-withdrawing characteristics or enhanced lipophilicity into the target molecules.
For chemists and procurement managers seeking to buy these advanced intermediates, selecting a supplier that guarantees purity and consistency is critical. NINGBO INNO PHARMCHEM CO.,LTD. prides itself on stringent quality control and a robust supply chain. This ensures that when you source 2-Iodo-4-(trifluoromethyl)benzoic acid from us, you receive a product that meets rigorous specifications, thereby enhancing the efficiency and success rate of your catalytic reactions. We offer competitive pricing and are happy to provide samples for your evaluation.
By leveraging our expertise as a chemical manufacturer, NINGBO INNO PHARMCHEM CO.,LTD. aims to be your preferred partner for all your iodo-aromatic intermediate needs. We understand the critical role these compounds play in cutting-edge research and development. Contact us today to learn more about how our high-quality 2-Iodo-4-(trifluoromethyl)benzoic acid can facilitate your next breakthrough in catalytic cross-coupling reactions.
Manufacturing Facilities
Professional Export Experience
to Global Customers
1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
2. Own R&D laboratory, pilot platform and large-scale production workshop, which can meet the audit requirements of global customers;
3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
A: Our payment terms: Small or sample order: T/T IN ADVANCE. Commercial order: First order should be by T/T IN ADVANCE or L/C at sight, and following orders T/T 30~90days is acceptable subject to approval of credit application.
