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The pharmaceutical industry relies on a complex network of chemical intermediates to produce life-saving and life-enhancing medications. Among these, 3-Amino-3-azabicyclo[3.3.0]octane hydrochloride (CAS 58108-05-7) holds a significant position as a key intermediate in the synthesis of Gliclazide. Gliclazide is a well-established oral antidiabetic drug belonging to the sulfonylurea class, widely used globally to manage type 2 diabetes mellitus. Understanding the chemical properties and manufacturing importance of this intermediate is vital for professionals involved in pharmaceutical production and supply chain management.
Chemically, 3-Amino-3-azabicyclo[3.3.0]octane hydrochloride is a bicyclic organic compound characterized by a fused ring system containing nitrogen atoms and an amine functional group, presented as a hydrochloride salt. Its molecular formula is C7H15ClN2, with a molecular weight of approximately 162.660 g/mol. The compound typically appears as an off-white to pale yellow crystalline powder, with a defined melting point range of 170-174 °C (lit.), though specific batches often exhibit a narrower range like 168.0-171.5 °C upon testing. These physical and chemical characteristics are crucial for its handling, storage, and reaction efficiency in subsequent synthesis steps.
The utility of 3-Amino-3-azabicyclo[3.3.0]octane hydrochloride as a Gliclazide intermediate stems from its ability to participate in specific chemical reactions that form the core structure of the Gliclazide molecule. The efficient and high-purity synthesis of this intermediate is therefore a prerequisite for producing quality Gliclazide. Manufacturers, particularly those in China with advanced chemical synthesis capabilities, focus on optimizing reaction conditions to achieve high yields and minimize side products. This dedication to quality ensures that the intermediate meets stringent pharmaceutical standards, including strict limits on impurities like 2-nitroso-octahydrocyclopenta[c]pyrrole, which must be kept below 20 ppm.
For pharmaceutical companies, identifying a reliable manufacturer and supplier of 3-Amino-3-azabicyclo[3.3.0]octane hydrochloride is essential for a stable production process. The global demand for Gliclazide, driven by the increasing incidence of diabetes, means that consistent and cost-effective sourcing of this intermediate is a strategic imperative. NINGBO INNO PHARMCHEM CO.,LTD. plays a crucial role in this supply chain, offering this vital intermediate with guaranteed purity and competitive pricing. We are proud to contribute to global health by providing the building blocks for essential medications. We invite potential buyers to contact us for detailed product information, quotations, and to discuss your specific requirements for bulk purchases.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
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