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For researchers and chemists engaged in advanced organic synthesis and pharmaceutical development, understanding the fundamental properties of key intermediates is critical. 4-Amino-3,5-dichloroacetophenone, identified by CAS number 37148-48-4, is one such compound, widely recognized for its utility in creating more complex molecules. This article explores its essential chemical properties and primary applications.
Chemically, 4-Amino-3,5-dichloroacetophenone (C8H7Cl2NO) is characterized by its acetophenone structure with amino and chlorine substituents. Its molecular weight is approximately 204.05 g/mol. Physically, it typically presents as a yellow or off-white crystalline powder. A key specification for this intermediate is its assay, usually provided as 99% minimum purity, ensuring minimal interference from impurities in synthesis reactions. The melting point, a common indicator of purity, is generally reported in the range of 162-166 °C. Understanding its solubility profile – slightly soluble in DMSO and methanol, insoluble in cold water, but soluble in organic solvents like ethanol, ether, and benzene – is also crucial for its practical use.
The primary application of 4-Amino-3,5-dichloroacetophenone lies in its role as an intermediate in organic synthesis. It is particularly noted for its use in the preparation of pharmaceuticals, including the synthesis of drugs for respiratory conditions. Beyond pharmaceuticals, it finds utility in biochemical research, contributing to the advancement of life sciences through the development of novel compounds and reaction pathways.
When considering the purchase of 4-Amino-3,5-dichloroacetophenone, it is advisable to seek out established manufacturers and suppliers who can guarantee these specifications. As a professional chemical supplier in China, we are committed to providing high-quality intermediates that meet stringent purity requirements. We offer this vital chemical for purchase, supporting both research laboratories and industrial clients. Ensuring you buy from a trusted source for CAS 37148-48-4 is fundamental for the success of your synthesis projects.
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