For scientists and procurement specialists engaged in chemical synthesis and drug discovery, a thorough understanding of an intermediate's properties is essential. This article delves into the chemical profile of 2-[2-(3-Methoxyphenyl)ethyl]phenol, identified by CAS number 167145-13-3, focusing on its characteristics and relevance for research and development (R&D) purposes.

Chemical Identity and Properties

2-[2-(3-Methoxyphenyl)ethyl]phenol, with the molecular formula C15H16O2 and a molecular weight of approximately 228.29 g/mol, is a fine chemical that finds its primary utility as a pharmaceutical intermediate. Its structure features a phenol group and a methoxy-substituted phenyl group linked by an ethyl chain. Key physical properties often cited include:

• Appearance: Typically described as a white solid.
• Melting Point: Ranges from 45.0 to 49.0 °C, indicating it is a solid at standard room temperature.
• Solubility: Slightly soluble in solvents like chloroform and methanol, which is a common characteristic for organic molecules of this type.
• Purity: Often available with a high purity, commonly specified as ≥99%.

These properties are critical for R&D scientists to consider when designing synthesis routes or handling the material in laboratory settings. The consistent availability of high-purity material from a trusted manufacturer is key for reproducible research outcomes.

Synthesis Relevance and Applications

The principal application of 2-[2-(3-Methoxyphenyl)ethyl]phenol lies in its role as a precursor in the synthesis of sarpogrelate hydrochloride. Sarpogrelate hydrochloride is a pharmaceutical compound known for its role as a 5-HT2A receptor antagonist and an antiplatelet agent, making it important in the treatment of cardiovascular conditions. The synthesis of such complex APIs requires intermediates that are precisely manufactured to yield the desired stereochemistry and purity.

For R&D teams, this intermediate offers a starting point for various chemical transformations. Its functional groups – the phenol hydroxyl and the ether linkage – allow for a range of reactions, including esterification, etherification, or further aromatic substitutions. This versatility makes it a valuable tool in the exploration of new chemical entities for drug discovery, potentially leading to novel therapeutic agents beyond cardiovascular applications.

Sourcing for R&D Needs

Researchers and procurement managers looking to buy 2-[2-(3-Methoxyphenyl)ethyl]phenol for R&D purposes should prioritize suppliers who can offer:

• Small to Medium Quantities: R&D often requires smaller quantities for initial screening and optimization.
• Detailed Technical Data: Access to NMR, IR, and mass spectrometry data can be invaluable for confirming identity and purity.
• Responsive Customer Service: For any technical queries or specific requirements, a responsive supplier is essential.

As a dedicated supplier of fine chemicals, we provide 2-[2-(3-Methoxyphenyl)ethyl]phenol (CAS 167145-13-3) with stringent quality controls. We aim to support the scientific community by offering this vital intermediate, enabling groundbreaking research and development in the pharmaceutical sector. If your R&D projects require this compound, we invite you to inquire about our product and pricing to ensure your research progresses smoothly.