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For professionals involved in chemical synthesis, understanding the precise properties of raw materials is fundamental to successful formulation and development. 2-Methyl-2-propyl-1,3-propanediol, identified by CAS number 78-26-2, is a chemical compound that holds significant importance, particularly within the pharmaceutical industry. Its unique molecular structure dictates its reactivity and applications, making it a sought-after intermediate. This article delves into the chemical profile, properties, and key uses of this versatile diol, and provides insights for those looking to buy it.
Chemical Identity and Properties
2-Methyl-2-propyl-1,3-propanediol is an alkyl diol characterized by its molecular formula C7H16O2 and a molecular weight of approximately 132.20 g/mol. It is typically presented as a white, crystalline solid, with a melting point ranging from 56-59 °C. This property makes it relatively easy to handle and store as a solid, contrasting with many liquid organic compounds. Its solubility is noted as slight in chloroform and methanol, indicating specific solvent compatibility requirements for its use in reactions or purification.
Key Physical and Chemical Characteristics:
Primary Applications in Synthesis
The most significant application of 2-Methyl-2-propyl-1,3-propanediol is its role as a crucial intermediate in the synthesis of pharmaceutical compounds. It is a precursor to dicarbamate derivatives, which are the active ingredients in drugs like Meprobamate (an anxiolytic) and Carisoprodol (a muscle relaxant). The presence of two hydroxyl groups (-OH) allows for its efficient conversion into these therapeutic agents. For pharmaceutical manufacturers needing to buy this intermediate, ensuring the specified purity and consistency is vital for regulatory compliance and product efficacy.
Sourcing and Quality Considerations
When procuring 2-Methyl-2-propyl-1,3-propanediol, whether for research or large-scale manufacturing, it is imperative to source from reputable chemical suppliers. Manufacturers in China are a common and cost-effective source for such intermediates. When you decide to buy, pay close attention to the supplier's specifications, particularly the purity percentage (often reported as ≥98.0% GC) and the availability of analytical documentation like Certificates of Analysis (CoA). These documents confirm that the product meets the required standards for your specific application. Choosing a supplier that provides consistent quality and reliable logistics is key to a smooth operational workflow.
In summary, 2-Methyl-2-propyl-1,3-propanediol (CAS 78-26-2) is a valuable chemical intermediate with a well-defined profile and critical pharmaceutical applications. Understanding its physical and chemical properties, coupled with strategic sourcing from reliable manufacturers, ensures that your synthesis projects benefit from high-quality materials.
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