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The precise chemical and physical characteristics of pharmaceutical intermediates are fundamental to successful drug synthesis. For the production of Rosuvastatin Calcium, a medication widely used to manage cholesterol, the intermediate 3-Bromomethyl-2-cyclopropyl-4-(4-fluorophenyl)quinoline (CAS: 154057-56-4) plays a crucial role. Understanding its detailed profile is vital for R&D scientists, formulators, and procurement specialists.
This organic compound is defined by its molecular formula, C19H15BrFN, and a molecular weight of 356.23200. These fundamental identifiers ensure that the correct chemical entity is being sourced. The appearance of the intermediate is typically a white to off-white crystalline powder, which is a common and desirable form for handling and reaction in pharmaceutical manufacturing. High-purity suppliers, such as those found among China's leading chemical manufacturers, consistently provide material meeting this description with an assay of ≥98.0%.
Further critical physical properties include its density of 1.461, a boiling point of 467.62ºC, and a flash point of 236.608ºC. These figures are important for process engineers and safety officers when designing synthesis protocols, ensuring appropriate reaction conditions, and implementing safe storage and handling procedures. The presence of bromine and fluorine in its structure also hints at its reactivity and suitability for specific types of organic transformations.
For pharmaceutical companies looking to buy 3-Bromomethyl-2-cyclopropyl-4-(4-fluorophenyl)quinoline, partnering with a supplier that provides comprehensive technical data sheets alongside their product is a significant advantage. This detailed information allows for better integration into complex synthesis routes and adherence to quality control protocols. Reliable manufacturers, including those from China, often provide extensive documentation to support their product's specifications and compliance.
In essence, the chemical profile of 3-Bromomethyl-2-cyclopropyl-4-(4-fluorophenyl)quinoline is more than just a set of numbers and descriptions; it's a guarantee of quality and a blueprint for its effective use in creating essential medications like Rosuvastatin Calcium. Ensuring that your sourcing partners provide detailed and accurate chemical profiles is paramount for successful pharmaceutical development and manufacturing.
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