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The Chemical Profile and Applications of 4,5-Dimethyl-2-Isobutyl-3-Thiazoline

In the realm of specialty chemicals, understanding the intricate properties and applications of individual compounds is crucial for innovation. 4,5-Dimethyl-2-Isobutyl-3-Thiazoline, identified by its CAS number 65894-83-9, is a prime example of an organic intermediate with significant value, particularly within the flavor and fragrance industries.

Chemically, this compound belongs to the thiazoline family, characterized by a five-membered ring containing both sulfur and nitrogen atoms. Its molecular formula is C9H17NS, with a molecular weight of approximately 171.3 g/mol. The presence of the isobutyl and dimethyl groups influences its reactivity and physical properties. Sources indicate a boiling point of around 208°C at atmospheric pressure and a density of approximately 1.487 g/mL at 25°C. The compound typically presents as a clear liquid, often with a light yellow to green hue, and possesses a distinctive aroma.

The sensory profile of 4,5-Dimethyl-2-Isobutyl-3-Thiazoline is what makes it highly sought after. Described as having notes of green nut skin, sulfurous undertones, and hints of burnt cocoa and corn, it is a powerful flavor enhancer. This complex aroma contributes significantly to the characteristic tastes of roasted nuts, popcorn, and fried peanuts, making it an indispensable ingredient for flavor houses aiming to replicate or enhance these natural tastes in food products. Its designation as FEMA GRAS (FEMA number 3621) underscores its safety for use in food applications at appropriate levels.

Beyond its primary role in food flavoring, this thiazoline derivative is also valued in the cosmetic and perfumery sectors. Its unique scent can add intriguing nuances to fragrance compositions, providing depth and sophistication. Furthermore, in the broader field of organic chemistry, compounds like 4,5-Dimethyl-2-Isobutyl-3-Thiazoline serve as important building blocks. Their specific structural features and reactivity allow for participation in various chemical reactions, enabling the synthesis of more complex molecules for pharmaceutical or material science applications. Researchers looking for specific organic intermediates to facilitate their synthesis pathways can often find reliable sourcing options from established chemical suppliers.

For businesses aiming to procure this compound, understanding the available specifications and sourcing options is important. Whether seeking bulk quantities for industrial production or smaller amounts for research and development, identifying a dependable manufacturer is key. Exploring the market for this specific CAS number will reveal various suppliers, each offering different grades and packaging options. When considering the price, it's advisable to engage with multiple reputable flavor and fragrance intermediate suppliers to ensure competitive terms. A direct inquiry about purchase or requesting a quote from established manufacturers in China is a common and effective strategy for obtaining this valuable chemical intermediate.

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