Ethyl 2-oxo-4-phenylbutyrate, identified by its CAS number 64920-29-2, is a chemical compound of significant importance within the pharmaceutical industry. Its precise chemical structure and properties make it an invaluable intermediate for the synthesis of various therapeutic agents. Understanding this chemical profile is essential for researchers, formulators, and procurement specialists looking to leverage its capabilities. We, as a dedicated manufacturer and supplier, offer this high-quality intermediate to meet your development needs.

The compound is scientifically known as Ethyl 2-oxo-4-phenylbutanoate, and it presents as a light yellow oily liquid. Its molecular formula is C12H14O3, with a molecular weight of approximately 206.24 g/mol. These fundamental identifiers are crucial for chemical calculations and reactions. Key physical properties, vital for process design and handling, include a reported boiling point of around 132°C at 2 mmHg and a density of approximately 1.091 g/mL at 25°C. The refractive index, typically noted around 1.504, is also a useful parameter for quality control. Its solubility in common organic solvents like chloroform and ethyl acetate facilitates its use in various reaction and purification protocols.

Chemically, Ethyl 2-oxo-4-phenylbutyrate is classified as an aliphatic α-ketoester. This functional group arrangement renders it a versatile building block in organic synthesis. It readily participates in reactions that are crucial for constructing complex molecular architectures found in pharmaceuticals. For instance, its ability to undergo transformations that lead to chiral alcohols makes it a critical precursor in the asymmetric synthesis of enantiomerically pure drug compounds.

The primary application of Ethyl 2-oxo-4-phenylbutyrate lies in its role as an intermediate for producing significant pharmaceutical products. It is indispensable in the synthesis of Lisinopril, a widely used ACE inhibitor for managing hypertension. Furthermore, it is a key precursor for Cilastatin, a compound that significantly boosts the efficacy of certain antibiotics by inhibiting their enzymatic breakdown in the body. These applications highlight the compound's profound impact on treating cardiovascular diseases and enhancing antibacterial treatments. When you decide to purchase this intermediate, you are investing in the development of these critical healthcare solutions.

For businesses seeking to integrate Ethyl 2-oxo-4-phenylbutyrate into their manufacturing processes, sourcing from a reputable manufacturer like us, a dedicated supplier in China, ensures adherence to strict quality standards, often with purity levels of 95.0% and above. This commitment to quality is vital for pharmaceutical applications. We provide this essential chemical at a competitive price, supporting innovation and accessibility in healthcare worldwide. Contact us to learn more about how we can fulfill your requirements.