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The Chemical Profile: Exploring 2-Amino-1-(4-nitrophenyl)-1,3-propanediol's Properties and Uses

The intricate world of organic chemistry is populated by compounds whose unique structures and properties unlock possibilities across various scientific and industrial domains. 2-Amino-1-(4-nitrophenyl)-1,3-propanediol, known by its CAS number 119-62-0, stands as a testament to this, offering a valuable profile for applications ranging from pharmaceutical synthesis to broader organic chemistry research.

At its core, 2-Amino-1-(4-nitrophenyl)-1,3-propanediol is characterized by its molecular formula, C9H12N2O4, and a molecular weight of 212.20300 g/mol. It typically presents as a white to light yellow crystalline powder, a form that signifies its processed state and ease of handling in laboratory and industrial settings. The compound's physical properties are noteworthy: it exhibits a density of 1.41 g/cm³, a relatively high melting point of 163-165°C, and a substantial boiling point of 451.9°C at 760 mmHg. Its flash point is recorded at 227.1°C, indicating a degree of thermal stability and a relatively low flammability risk. Furthermore, its vapor pressure is exceedingly low at 5.92E-09 mmHg at 25°C, suggesting minimal volatility under standard conditions, which is beneficial for storage and handling safety.

The chemical structure of 2-Amino-1-(4-nitrophenyl)-1,3-propanediol is key to its utility. It features a nitro group, an amino group, and two hydroxyl groups attached to a propanediol backbone. This arrangement makes it a versatile building block in organic synthesis. Its most significant application is as an intermediate in the production of chloramphenicol, a critical antibiotic. The amino and hydroxyl functionalities are essential for the chemical reactions that form the chloramphenicol molecule. The high purity, typically exceeding 98.0%, of this intermediate is crucial for ensuring the quality and effectiveness of the resulting pharmaceutical product. Researchers also value its predictable reactivity for developing novel compounds or refining existing synthesis pathways.

Beyond its established role in pharmaceutical manufacturing, the inherent reactivity of 2-Amino-1-(4-nitrophenyl)-1,3-propanediol suggests potential applications in material science or the development of specialty chemicals. The presence of multiple functional groups allows for diverse chemical modifications, opening avenues for innovation. For industries requiring this compound, sourcing from reputable manufacturers, such as those found in China, is often a strategic move. Companies like Ningbo Inno Pharmchem Co., Ltd. provide a spectrum of fine chemicals and intermediates, underscoring the accessibility of these specialized materials. Understanding the detailed chemical profile and reliable sourcing strategies for 2-Amino-1-(4-nitrophenyl)-1,3-propanediol is fundamental for advancing research and development in the chemical sciences.

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