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The Chemical Profile and Significance of N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester

Understanding the precise chemical profile of key intermediates is fundamental to successful synthesis in the pharmaceutical and fine chemical industries. N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester, with the CAS number 4779-31-1, is a compound that embodies this principle, serving as a crucial building block for a wide array of complex molecules. Its well-defined chemical structure and physical properties make it an indispensable tool for chemists engaged in advanced organic synthesis.

The chemical name, N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester, along with its alternative name (3S)-4-oxo-4-phenylmethoxy-3-(phenylmethoxycarbonylamino)butanoic acid, provides insight into its structure. It is derived from the amino acid L-aspartic acid, with the amine group protected by a carbobenzyloxy (Cbz) moiety and the alpha-carboxyl group esterified with a benzyl group. The molecular formula C19H19NO6 and molecular weight of 357.35700 are key identifiers. These structural features are critical for its role as a pharmaceutical intermediate, enabling selective reactions and controlled deprotection steps in complex synthesis.

The physical characteristics of N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester further underscore its utility. It typically appears as a white powder, a stable form that facilitates handling and storage. Key physical properties include a melting point of 80-86°C, a density of 1.293 g/cm³, and a refractive index of 1.581. These parameters are important for quality control and for predicting its behavior in various chemical processes. For those looking to buy N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester, these specifications are vital for ensuring the suitability of the material for their specific research or production needs.

The applications of this compound are primarily centered around its use in pharmaceutical synthesis. It serves as a critical component in the construction of peptides and other biologically active molecules, making it invaluable for drug discovery and development. Its precise structure allows for the precise incorporation of aspartic acid derivatives into therapeutic candidates, particularly in the development of specialized treatments such as anticancer agents and neuroprotective compounds. The demand for reliable N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester synthesis is therefore high.

Global sourcing of this compound is efficient, with many reputable manufacturers and suppliers available, particularly within China. When selecting an N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester supplier, prioritizing those with stringent quality control measures and a consistent supply record is crucial. This ensures that the material meets the high purity standards required for pharmaceutical applications, typically ≥98%.

In conclusion, N-Carbobenzyloxy-L-aspartic Acid 1-Benzyl Ester is a vital chemical intermediate with a well-defined profile that supports critical advancements in pharmaceutical synthesis and drug discovery. Its structural versatility and high purity make it an essential component for chemists aiming to create sophisticated and effective medicinal compounds.

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