For chemists, researchers, and procurement specialists in the chemical and pharmaceutical industries, a deep understanding of a compound's chemical properties is fundamental to its effective application and safe handling. 4-(Dimethylamino)phenol Hydrochloride (CAS 5882-48-4) is one such compound, a versatile intermediate with specific characteristics that dictate its use in various synthesis processes.

Molecular Structure and Formula

The molecular formula for 4-(Dimethylamino)phenol Hydrochloride is C8H11NO•ClH. Its structure features a phenol ring substituted with a dimethylamino group at the para position, forming the basic 4-(dimethylamino)phenol moiety. The hydrochloride salt formation means it exists as the protonated amine cation and a chloride anion. This ionic nature influences its solubility and stability. The molecular weight is approximately 173.64 g/mol.

Key Physical and Chemical Properties

Based on available data and common industry specifications, the properties of 4-(Dimethylamino)phenol Hydrochloride include:

• Appearance: Typically described as a white powder. This physical form is standard for many solid chemical intermediates, indicating it is stable under ambient conditions.
• Purity: Commonly supplied with a purity of 98% (by HPLC), ensuring a high degree of suitability for synthesis and formulation without significant interfering impurities.
• Solubility: As a hydrochloride salt, it generally exhibits good solubility in polar solvents such as water and alcohols, which is advantageous for solution-phase reactions.
• Melting Point: While specific ranges can vary slightly between suppliers, it is often cited around 141-147°C. This relatively moderate melting point is typical for organic salts and provides a useful parameter for identification and quality control.
• Boiling Point: The boiling point is often listed as approximately 259.7°C at 760 mmHg, though decomposition may occur at elevated temperatures.
• Flash Point: A flash point of 135.6°C indicates that it is combustible but not highly flammable, requiring standard precautions for handling organic solids.

Safety and Handling Considerations

When handling 4-(Dimethylamino)phenol Hydrochloride, standard laboratory safety protocols should be followed. This includes wearing appropriate personal protective equipment (PPE) such as gloves, eye protection, and lab coats. Safety Data Sheets (SDS) provided by the manufacturer or supplier offer detailed information on potential hazards, first-aid measures, and safe storage. Proper storage, often in an inert atmosphere at room temperature, is recommended to maintain its quality and integrity over time.

For those looking to purchase this compound, understanding these chemical properties is vital for selecting the right grade and ensuring it meets the technical requirements of their specific application. Whether for cosmetic formulations, pharmaceutical synthesis, or other organic chemistry endeavors, a solid grasp of its characteristics, combined with a reliable sourcing partner for CAS 5882-48-4, is key to success.