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The Chemical Properties and Applications of 2-Amino-5-nitrobenzophenone

2-Amino-5-nitrobenzophenone, known by its CAS number 1775-95-7, is a compound that holds significant interest within the chemical community due to its distinct molecular structure and reactive potential. As a fine chemical intermediate, it is characterized by its appearance as a beige solid, a physical state that suggests a crystalline structure. With a melting point typically recorded between 166-168°C, it indicates a stable solid compound under normal laboratory conditions. Chemically, its formula C13H10N2O3 reveals a benzophenone backbone substituted with both an amine (-NH2) group and a nitro (-NO2) group. These functional groups are key to its reactivity, making it a versatile precursor in organic synthesis.

The amine group can participate in nucleophilic reactions, amide formations, or diazotization, while the nitro group can be reduced to an amine, undergo nucleophilic aromatic substitution under certain conditions, or influence the electronic properties of the aromatic rings. Its limited solubility in water, as noted in technical data, implies that its reactions are typically carried out in organic solvents such as methanol, ethanol, DMSO, or chloroform, which are common in fine chemical synthesis. This solubility profile is typical for many aromatic organic compounds of this size and polarity.

The applications of 2-Amino-5-nitrobenzophenone are primarily centered around its use as a building block in the synthesis of more complex molecules. It is frequently employed in the preparation of pharmaceutical intermediates, contributing to the development of novel drug candidates. Furthermore, its structure can be leveraged in the creation of specialty chemicals, potentially finding use in areas like photochemistry, material science, or as a component in advanced organic electronic materials. Companies engaged in chemical research often procure this compound to explore new synthetic routes and develop innovative chemical entities. Understanding these properties is essential for chemists and procurement specialists aiming to effectively utilize or source this valuable intermediate.

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