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Typically presented as a colorless to pale yellow transparent liquid, Methyl 4-chloro-3-oxo-butanoate has a molecular weight of 150.56. Its physical state at room temperature is liquid, with a melting point around 14-16 °C. The boiling point, often cited at 85 °C/4 mmHg, indicates its volatility under reduced pressure, a common consideration for reaction and purification processes. The density is approximately 1.305 g/mL at 25 °C, and its refractive index is around 1.456 (n20/D).
From a synthetic perspective, the chlorine atom in Methyl 4-chloro-3-oxo-butanoate is labile and can be readily displaced in nucleophilic substitution reactions. The beta-keto ester moiety allows for enolization and subsequent electrophilic attack, or it can undergo decarboxylation under certain conditions. These reactive centers make it a valuable precursor for building carbon-carbon bonds and introducing specific functionalities into larger molecules.
Its primary application lies in its role as an intermediate in the synthesis of agrochemicals, notably insecticides. It is also recognized for its potential use in pharmaceutical synthesis, contributing to the creation of diverse drug molecules. For R&D scientists and procurement managers, identifying reliable manufacturers and suppliers who can guarantee consistent quality and availability is paramount. When you aim to buy Methyl 4-chloro-3-oxo-butanoate, verifying its purity (typically ≥98.0%) and understanding its stability (it's noted as moisture-sensitive) are crucial steps.
The chemical industry relies on intermediates like Methyl 4-chloro-3-oxo-butanoate to drive innovation. Whether for developing new crop protection agents or exploring novel pharmaceutical compounds, having access to well-characterized and high-purity materials is essential. We are committed to providing this vital intermediate to researchers and manufacturers, ensuring competitive pricing and dependable supply from our facilities. Partner with us for your organic synthesis needs and explore the full potential of this versatile chemical.
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