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The utility of any chemical intermediate in pharmaceutical synthesis hinges on its specific chemical and physical properties. For 1-Acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-indole-7-carbonitrile (CAS: 175837-01-1), these characteristics are precisely what make it a valuable building block for Silodosin. As a leading supplier in the industry, NINGBO INNO PHARMCHEM CO.,LTD. provides this essential compound with well-defined properties to ensure successful synthesis outcomes.
Physically, 1-Acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-indole-7-carbonitrile is typically described as a brown powder. This form is convenient for handling, storage, and precise dosing in manufacturing processes. Its assay of ≥95.0% signifies a high level of purity, which is critical for minimizing side reactions and ensuring the efficacy and safety of the final drug product. Key physicochemical properties reported include a density of approximately 1.2 g/cm³, a boiling point of around 498.6 °C at 760 mmHg, and a flash point of about 255.3 °C. These parameters are important for process safety and optimization.
Chemically, the presence of the indole ring system, an acetyl group, an aminopropyl side chain, and a carbonitrile functional group contribute to its reactivity. This specific arrangement of functional groups is precisely what is needed for its role as a Silodosin intermediate. Understanding these chemical properties allows formulators and process chemists to design efficient synthetic routes. For companies looking to buy this compound, partnering with a reputable manufacturer like NINGBO INNO PHARMCHEM CO.,LTD. ensures access to consistent material that meets these exacting chemical property standards.
The application of 1-Acetyl-5-(2-aminopropyl)-2,3-dihydro-1H-indole-7-carbonitrile is primarily in the synthesis of Silodosin, an alpha1a-adrenoceptor antagonist used in the treatment of benign prostatic hyperplasia. Its role as a precursor highlights its importance in the pharmaceutical supply chain. If your company requires this critical intermediate, NINGBO INNO PHARMCHEM CO.,LTD. is your trusted source in China, offering reliable supply and competitive prices.
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