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2,3-Difluorobenzyl Bromide (CAS: 113211-94-2) is a valuable organic compound characterized by its benzyl bromide structure with two fluorine atoms substituted on the aromatic ring at the 2 and 3 positions. This specific arrangement of fluorine atoms imparts unique chemical properties that are highly advantageous in various synthetic applications, particularly within the pharmaceutical and fine chemical industries.
Understanding its chemical properties is key for chemists looking to buy this intermediate. It typically appears as a clear, colorless to light yellow liquid with a boiling point around 190.5 °C and a density of approximately 1.628 g/mL. The presence of the bromine atom makes the benzyl carbon susceptible to nucleophilic substitution reactions, a primary mode of reactivity that allows for the facile introduction of the 2,3-difluorobenzyl group into various molecular scaffolds. This reactivity is central to its utility as a building block.
The fluorine atoms themselves significantly influence the molecule's electronic properties and can enhance the biological activity of downstream products. Fluorine's high electronegativity and small atomic radius can alter pKa values, improve lipophilicity, and increase metabolic stability by blocking sites prone to oxidative degradation. This makes 2,3-Difluorobenzyl Bromide an attractive intermediate for designing pharmaceuticals with improved efficacy and bioavailability.
As a dedicated supplier and manufacturer, we ensure that our 2,3-Difluorobenzyl Bromide meets stringent purity standards, typically ≥98%. This high purity is essential for predictable reaction outcomes in complex organic syntheses. Our clients, often R&D scientists and procurement specialists, rely on us for consistent quality and timely delivery from our facilities in China. Whether you need it for the synthesis of novel APIs, advanced agrochemicals, or specialized materials, this compound is a dependable choice.
For any inquiries regarding the chemical properties, handling, or to request a quote for bulk quantities, please contact our expert team. We are here to support your research and development needs with high-quality chemical intermediates.
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1. 20 years of R&D, manufacturing and sales experience, serving customers in 60 countries and regions around the world;
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3. We can satisfy customers' perfect transition from small scale lab requirements (gram level) to commercialization requirements (hundred tons level).
A: We don't have Minimum Order Quantity, exact quantity should be provided before quotation for us to calculate the exact cost.
A: We don't provide free samples due to lots of request and expensive international courier's cost, we can deduct the sample charge after commercial order placed.
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