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The Chemical Properties and Applications of 2-Fluoroaniline

2-Fluoroaniline, a chemical compound with the CAS number 348-54-9, is a versatile organic intermediate that finds extensive application across several key industrial sectors, including pharmaceuticals, agrochemicals, and dyes. Understanding its chemical properties is fundamental to leveraging its full potential in synthesis and product development.

Physically, 2-Fluoroaniline is described as a yellow liquid, with a high purity level, often exceeding 99% by GC assay. Its molecular formula is C6H6FN, and it possesses a characteristic chemical structure that includes both an amine group and a fluorine atom attached to a benzene ring. This specific arrangement contributes to its reactivity and usefulness as a synthetic building block.

The compound's properties include a boiling point around 182-183 °C and a melting point of approximately -29 °C, indicating its liquid state under standard conditions. It is soluble in organic solvents like ethanol and ether but has limited solubility in water. Safety data indicates it is a hazardous substance, requiring careful handling, appropriate personal protective equipment (PPE), and storage in a cool, dry place, away from ignition sources.

The primary utility of 2-Fluoroaniline lies in its role as an intermediate. In the pharmaceutical industry, it's used in the synthesis of various drug molecules, contributing to enhanced bioavailability and therapeutic efficacy. For agrochemical manufacturers, it serves as a precursor for potent herbicides and pesticides, aiding in effective crop protection. The dye industry utilizes it in the creation of vibrant and stable colorants. When considering a purchase, manufacturers and researchers should inquire about the specific grades and packaging options available from suppliers to best suit their application needs.

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