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The Chemical Properties and Applications of 3-Amino-5-bromobenzotrifluoride

Understanding the intrinsic chemical properties of a compound is fundamental to leveraging its potential in various industrial and scientific applications. 3-Amino-5-bromobenzotrifluoride, identified by CAS number 54962-75-3, is a fluorinated organic compound with a unique molecular structure that dictates its reactivity and utility. As a sought-after organic synthesis intermediate, its physical and chemical characteristics are key to its value.

This compound typically presents as a colorless to light yellow liquid, with a density around 1.7 g/cm³. Its boiling point is approximately 231.2 °C at 760 mmHg, indicating moderate volatility. The molecular formula C7H5BrF3N and a molecular weight of 240.020 further define its composition. The presence of the bromine atom and the electron-withdrawing trifluoromethyl group influences the reactivity of the amine functionality, making it a versatile substrate for various chemical transformations. These properties are crucial for chemists looking to buy and utilize it effectively.

The primary application of 3-Amino-5-bromobenzotrifluoride lies in its role as a pharmaceutical intermediate. It is a critical precursor in the synthesis of Nilotinib, a targeted therapy used in the treatment of chronic myeloid leukemia (CML). The precise structure and purity of this intermediate are vital for the successful and efficient production of such life-saving drugs. Beyond pharmaceuticals, it serves as a valuable building block in broader organic synthesis, enabling the construction of complex molecules for research and development in areas like agrochemicals and materials science.

For professionals in these fields, sourcing this compound reliably is essential. Identifying manufacturers and suppliers that guarantee high purity (≥98.0%) and offer consistent quality is a priority. When looking to purchase 3-Amino-5-bromobenzotrifluoride, consider suppliers who can provide detailed technical data and flexible packaging. The competitive pricing often available from Chinese manufacturers can make it a cost-effective choice for both R&D labs and large-scale production facilities.

In conclusion, the chemical properties of 3-Amino-5-bromobenzotrifluoride make it an indispensable intermediate in modern chemistry, particularly in the pharmaceutical industry. Its applications are vital for therapeutic advancements, and its sourcing requires attention to purity and reliability. By engaging with reputable chemical suppliers, you can secure this essential compound for your synthesis needs.

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