In the realm of fine chemicals, understanding the precise properties and potential applications of a compound is vital for successful integration into synthesis workflows. 4-(Trifluoromethoxy)phenyl Isothiocyanate, a molecule characterized by its distinctive trifluoromethoxy group and reactive isothiocyanate moiety, is a prime example of an intermediate that fuels innovation across various chemical disciplines. As a dedicated supplier and manufacturer in China, NINGBO INNO PHARMCHEM CO.,LTD. offers this compound, ensuring high purity and reliable availability for researchers and industrial chemists.

The fundamental chemical identity of 4-(Trifluoromethoxy)phenyl Isothiocyanate is defined by its molecular formula C8H4F3NOS and CAS number 64285-95-6. Physically, it presents as a colorless transparent liquid, with a reported density of 1.35 g/mL at 25°C and a boiling point range of 215-218°C. These properties are significant for handling, storage, and reaction optimization. The most notable feature is the trifluoromethoxy (-OCF3) group, which significantly alters the electronic distribution and lipophilicity of the phenyl ring, influencing the reactivity of the adjacent isothiocyanate group (-NCS).

The isothiocyanate group is a potent electrophile, readily undergoing addition reactions with a variety of nucleophiles. This inherent reactivity makes 4-(Trifluoromethoxy)phenyl Isothiocyanate an exceptionally useful building block for the synthesis of diverse organic structures. Key applications include:

• Pharmaceutical Synthesis: As a precursor for creating thiourea, thiocarbamate, and heterocyclic structures that are common motifs in drug molecules. The trifluoromethoxy group can enhance metabolic stability and binding affinity.
• Agrochemical Development: Its derivatives can be explored for their potential as pesticides, herbicides, or fungicides, leveraging the unique properties conferred by the fluorinated substituent.
• Material Science: Used in the synthesis of specialized polymers or functional materials where the trifluoromethoxy group contributes to desirable physical properties.

For entities looking to purchase 4-(Trifluoromethoxy)phenyl Isothiocyanate, NINGBO INNO PHARMCHEM CO.,LTD. provides a streamlined procurement process. We guarantee a product with an assay of ≥99.0%, ensuring that your synthesis results are accurate and reproducible. Understanding the price point for bulk quantities is essential for large-scale manufacturing, and we are competitive in this regard. Our commitment as a reliable supplier means you can count on timely deliveries and consistent product quality.

When planning your next synthesis project that requires this versatile intermediate, consider the advantages of working with NINGBO INNO PHARMCHEM CO.,LTD. We are equipped to provide the high-purity 4-(Trifluoromethoxy)phenyl Isothiocyanate you need to drive your chemical innovations forward. Reach out to us today to discuss your requirements and secure your supply of this critical organic synthesis component.