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Understanding the Chemical Properties and Applications of 5-Hydroxynicotinic Acid

For chemists and researchers in the field of organic chemistry, understanding the precise properties and applications of key intermediates is crucial for successful synthesis. 5-Hydroxynicotinic Acid, identified by its CAS number 27828-71-3, is one such compound that offers significant value as a versatile building block.

Chemical Profile of 5-Hydroxynicotinic Acid

5-Hydroxynicotinic Acid is a derivative of nicotinic acid, belonging to the class of pyridine compounds. Its molecular formula is C6H5NO3, with a molecular weight of approximately 139.11 g/mol. Key physical and chemical properties include:

  • Appearance: Typically supplied as a white to off-white or yellow powder.
  • Melting Point: A high melting point of around 299°C, indicating thermal stability.
  • Solubility: Often soluble in polar organic solvents like DMSO.
  • Structure: Features a pyridine ring substituted with a hydroxyl group at the 5-position and a carboxylic acid group at the 3-position.

These characteristics make it an ideal starting material for a variety of chemical transformations.

Key Applications in Chemical Synthesis

The unique structure of 5-Hydroxynicotinic Acid dictates its primary uses in various scientific disciplines:

  • Organic Synthesis: It is widely utilized as an organic intermediate, providing a functionalized pyridine scaffold for constructing more complex molecules. Researchers often seek to buy this compound for its versatility in coupling reactions, functional group modifications, and heterocyclic ring formations.
  • Pharmaceutical Intermediates: Its relevance extends to the pharmaceutical industry, where it serves as a building block for synthesizing various APIs or their precursors. The pyridine structure is prevalent in many therapeutic agents.
  • Biochemical Research: As a structural analog of nicotinic acid, it finds application in biochemical studies, particularly in investigating enzyme mechanisms and metabolic pathways.

Where to Buy 5-Hydroxynicotinic Acid

For scientists and procurement specialists looking to source 5-Hydroxynicotinic Acid, identifying a reliable manufacturer and supplier is crucial. Many companies offer this product, with varying levels of purity and service. When considering where to purchase, it is advisable to look for suppliers who:

  • Provide detailed specifications and Certificates of Analysis (CoA).
  • Offer competitive pricing, especially for bulk quantities.
  • Have a strong reputation for quality and customer support.
  • Are able to provide consistent supply chains, particularly if sourcing from a prominent manufacturer in China.

Ensuring you obtain high-quality 5-Hydroxynicotinic Acid (CAS 27828-71-3) from a trusted 5-hydroxynicotinic acid supplier is fundamental for achieving accurate and reproducible results in your chemical research and development endeavors.

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