In the realm of organic chemistry and pharmaceutical manufacturing, certain compounds serve as fundamental building blocks that enable the creation of complex and vital molecules. 6-Chlorooxindole (CAS: 56341-37-8) is one such compound, a crucial intermediate with significant applications, most notably in the pharmaceutical industry for the synthesis of Ziprasidone. Understanding its chemical properties and diverse applications is key for researchers and industry professionals looking to buy this compound.

Detailed Chemical Profile of 6-Chlorooxindole

6-Chlorooxindole, also identified by synonyms such as 6-chloro-2-oxo-1,2-dihydro-indole, is an organic chemical compound with the molecular formula C8H6ClNO and a molecular weight of 167.59200. It typically presents as a light brown crystalline powder. Its physical characteristics, such as a melting point of 195-199°C and a boiling point of 329°C, are important for handling and processing. The refractive index is noted as 1.601. Critically for its pharmaceutical use, it boasts an assay of ≥98.0% and a moisture content of ≤0.2%, ensuring a high degree of purity.

The synthesis of 6-Chlorooxindole itself is a multi-step process often starting from precursors like 4-chloro-2-nitrotoluene. The routes involve forming intermediate acids and subsequent reductive cyclization to achieve the desired oxindole structure. The meticulous control over these synthetic pathways by manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. ensures that the supplied 6-Chlorooxindole meets the exacting purity standards required for pharmaceutical applications. This focus on quality makes it a dependable intermediate for drug manufacturers.

Key Applications and Market Relevance

The most significant application of 6-Chlorooxindole is its role as a vital intermediate in the synthesis of Ziprasidone, an atypical antipsychotic used to treat schizophrenia and bipolar disorder. Its chemical structure is integral to forming the final API, making its reliable supply essential for pharmaceutical production. Beyond this primary use, research indicates potential applications in other areas, including the development of non-peptide MDM2 inhibitors for cancer therapy, highlighting its versatility as a chemical building block.

For businesses looking to procure 6-Chlorooxindole, understanding its market and sourcing options is crucial. As a dedicated manufacturer and supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers this intermediate with a commitment to quality and consistent supply. This makes them a valuable partner for pharmaceutical companies and research institutions worldwide seeking to buy this essential chemical. The competitive pricing and large-scale production capabilities from Chinese manufacturers further enhance their appeal in the global market.

In conclusion, 6-Chlorooxindole is a compound of significant industrial importance, particularly within the pharmaceutical sector. Its well-defined chemical properties and critical role in the synthesis of essential medications like Ziprasidone underscore the need for reliable sourcing. Manufacturers like NINGBO INNO PHARMCHEM CO.,LTD. play a key role in ensuring its availability to meet global demand.